The Radiation Therapy Oncology Group is a group of radiation research and clinical centers which conduct highly disciplined joint clinical investigations. The Group has the following objectives: a. To undertake clinical trials and other cooperative studies in an endeavor to advance knowledge of radiation therapy while improving the curative and palliative management of cancer. b. To improve the control of primary and regional disease. c. To reduce treatment morbidity and complications from radiation therapy, while maintaining control of primary and regional disease. d. To collaborate with other oncology disciplines to obtain data on optimal multimodality therapy, particularly in areas where radiation therapy play a major role. e. To develop and implement stringent quality control procedures in all group studies. f. To develop cancer control research projects of interest to the radiation therapy community. The RTOG serves as a research base for members of the Community Clinical Oncology Program (CCOP). The CCOP institutions participate in all phases of RTOG research.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
3U10CA037422-06S1
Application #
3558086
Study Section
Special Emphasis Panel (SRC (46))
Project Start
1983-09-30
Project End
1991-05-31
Budget Start
1990-06-25
Budget End
1991-05-31
Support Year
6
Fiscal Year
1990
Total Cost
Indirect Cost
Name
American College of Radiology
Department
Type
DUNS #
City
Philadelphia
State
VA
Country
United States
Zip Code
Ali, Arif N; Zhang, Peixin; Yung, W K Alfred et al. (2018) NRG oncology RTOG 9006: a phase III randomized trial of hyperfractionated radiotherapy (RT) and BCNU versus standard RT and BCNU for malignant glioma patients. J Neurooncol 137:39-47
Lawrence, Yaacov R; Moughan, Jennifer; Magliocco, Anthony M et al. (2018) Expression of the DNA repair gene MLH1 correlates with survival in patients who have resected pancreatic cancer and have received adjuvant chemoradiation: NRG Oncology RTOG Study 9704. Cancer 124:491-498
Raman, Srinivas; Ding, Keyue; Chow, Edward et al. (2018) Minimal clinically important differences in the EORTC QLQ-C30 and brief pain inventory in patients undergoing re-irradiation for painful bone metastases. Qual Life Res 27:1089-1098
Dormer, James D; Halicek, Martin; Ma, Ling et al. (2018) Convolutional Neural Networks for the Detection of Diseased Hearts Using CT Images and Left Atrium Patches. Proc SPIE Int Soc Opt Eng 10575:
Dormer, James D; Ma, Ling; Halicek, Martin et al. (2018) Heart Chamber Segmentation from CT Using Convolutional Neural Networks. Proc SPIE Int Soc Opt Eng 10578:
Michalski, Jeff M; Moughan, Jennifer; Purdy, James et al. (2018) Effect of Standard vs Dose-Escalated Radiation Therapy for Patients With Intermediate-Risk Prostate Cancer: The NRG Oncology RTOG 0126 Randomized Clinical Trial. JAMA Oncol 4:e180039
Seider, Michael J; Pugh, Stephanie L; Langer, Corey et al. (2018) Randomized phase III trial to evaluate radiopharmaceuticals and zoledronic acid in the palliation of osteoblastic metastases from lung, breast, and prostate cancer: report of the NRG Oncology RTOG 0517 trial. Ann Nucl Med 32:553-560
Basch, Ethan; Dueck, Amylou C; Rogak, Lauren J et al. (2018) Feasibility of Implementing the Patient-Reported Outcomes Version of the Common Terminology Criteria for Adverse Events in a Multicenter Trial: NCCTG N1048. J Clin Oncol :JCO2018788620
Regine, William F; Winter, Kathryn; Abrams, Ross A et al. (2018) Postresection CA19-9 and margin status as predictors of recurrence after adjuvant treatment for pancreatic carcinoma: Analysis of NRG oncology RTOG trial 9704. Adv Radiat Oncol 3:154-162
Konski, Andre; Bhargavan, Mytheryi; Owen, Jean et al. (2018) An Economic Analysis of Radiation Therapy Oncology Group 94-10: Cost-Efficacy of Concurrent vs. Sequential Chemoradiotherapy. J Radiat Oncol 7:195-201

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