The Columbia River Oncology Program (CROP), a Community Clinical Oncology Program (CCOP) currently in its 22nd year, is a consortium of four health care systems in the metropolitan Portland, Oregon/Vancouver, Washington area. These health care systems encompass: Adventist Medical Center, Legacy Health System, Providence Health System, and Southwest Washington Medical Center. CROP'S specific aims are: 1) Enhance the health of our community by providing and promoting cancer treatment, cancer prevention and cancer control research studies, 2) Seek opportunities to mirror the diversity of our community by providing complementary and holistic clinical research studies, 3) Advocate for and participate in clinical trials providing symptom management, improved quality of life, and palliative care for our cancer patient population, 4) Increase our physician alliances and commitments to clinical trials and increase accrual goals, and 5) Expand participation of minorities and the underserved population to participate in cancer prevention, cancer control and treatment studies. CROP currently affiliates with seven research bases: COG, MDACC, NCCTG, NSABP, RTOG, SWOG, and URCC. All are multi-specialty cooperative groups that supply CROP with NCI approved cancer prevention, cancer control and cancer treatment protocols. The established functioning operational status of CROP includes an Executive Board with representative committee structure, a central office, and actively participating hospital systems. The central office staff coordinates the administrative aspects of CROP, the large cancer prevention studies and quality improvement activities. The Clinical Trial Nurses and Clinical Research Associates employed by the consortium hospitals recruit patients to cancer control and treatment protocols collect and submit data to the research bases, participate in the quality improvement process, and actively participate in the research base meetings. Each organization employs a pharmacist to manage the investigational agents for CROP.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Cooperative Clinical Research--Cooperative Agreements (U10)
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Special Emphasis Panel (ZCA1-SRRB-Y (J1))
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O'Mara, Ann M
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Providence Portland Medical Center
United States
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Samlowski, Wolfram E; Moon, James; Witter, Merle et al. (2017) High frequency of brain metastases after adjuvant therapy for high-risk melanoma. Cancer Med 6:2576-2585
Goldkorn, Amir; Ely, Benjamin; Tangen, Catherine M et al. (2015) Circulating tumor cell telomerase activity as a prognostic marker for overall survival in SWOG 0421: a phase III metastatic castration resistant prostate cancer trial. Int J Cancer 136:1856-62
Blumenthal, Deborah T; Rankin, Cathryn; Stelzer, Keith J et al. (2015) A Phase III study of radiation therapy (RT) and O?-benzylguanine + BCNU versus RT and BCNU alone and methylation status in newly diagnosed glioblastoma and gliosarcoma: Southwest Oncology Group (SWOG) study S0001. Int J Clin Oncol 20:650-8
Ou, Sai-Hong Ignatius; Moon, James; Garland, Linda L et al. (2015) SWOG S0722: phase II study of mTOR inhibitor everolimus (RAD001) in advanced malignant pleural mesothelioma (MPM). J Thorac Oncol 10:387-91
Budd, George T; Barlow, William E; Moore, Halle C F et al. (2015) SWOG S0221: a phase III trial comparing chemotherapy schedules in high-risk early-stage breast cancer. J Clin Oncol 33:58-64
Smerage, Jeffrey B; Barlow, William E; Hortobagyi, Gabriel N et al. (2014) Circulating tumor cells and response to chemotherapy in metastatic breast cancer: SWOG S0500. J Clin Oncol 32:3483-9
Carson 3rd, William E; Unger, Joseph M; Sosman, Jeffrey A et al. (2014) Adjuvant vaccine immunotherapy of resected, clinically node-negative melanoma: long-term outcome and impact of HLA class I antigen expression on overall survival. Cancer Immunol Res 2:981-7
Kernstine, Kemp H; Moon, James; Kraut, Michael J et al. (2014) Trimodality therapy for superior sulcus non-small cell lung cancer: Southwest Oncology Group-Intergroup Trial S0220. Ann Thorac Surg 98:402-10
Allen, Jeffrey W; Moon, James; Redman, Mary et al. (2014) Southwest Oncology Group S0802: a randomized, phase II trial of weekly topotecan with and without ziv-aflibercept in patients with platinum-treated small-cell lung cancer. J Clin Oncol 32:2463-70
Goldkorn, Amir; Ely, Benjamin; Quinn, David I et al. (2014) Circulating tumor cell counts are prognostic of overall survival in SWOG S0421: a phase III trial of docetaxel with or without atrasentan for metastatic castration-resistant prostate cancer. J Clin Oncol 32:1136-42

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