The Southeast Cancer Control Consortium (SCCC) application is placed in response to the RFA: Community Clinical Oncology Program. The applicant is a consortium of communities in Eastern Tennessee, Southern Virginia, and North and South Carolina who seek to pool their experience to evolve a productive Community Clinical Oncology Program. The demography of the area reflects low population density, limited socioeconomic and educational development and a black to white population ratio of approximately twice the national average. These participating community oncologists have had experience in clinical trials under the program of the Piedmont Oncology Association (POA) with an accrual of over 750 patients during the past five years. The community team is supported by a local medical oncologist, a cancer committee and a trained oncology nurse protocol coordinator. Each community has participated in quality assurance activities as prescribed by the NCI-CTEP under both the POA and Cancer and Leukemia Group B (CALGB). The opportunity to develop, in association with local agencies, a productive cancer control program will focus on the specific stable population to include education for earlier treatment and compliance in therapy, as well as a program of school age and adult education in prevention. Specific attention will be given to reaching the underprivileged and the black populations. It is anticipated that this group will place 275 patients on clinical trial studies during the first year. The SCCC will develop group cancer control projects via the Oncology Research Center of Bowman Gray School of Medicine and National Cooperative groups (CALGB, NSABP) with which the SCCC is affiliated.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
1U10CA045808-01
Application #
3558709
Study Section
(SRC)
Project Start
1987-07-10
Project End
1990-05-31
Budget Start
1987-07-10
Budget End
1988-05-31
Support Year
1
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Southeast Cancer Control Consortium
Department
Type
DUNS #
876940532
City
Winston-Salem
State
NC
Country
United States
Zip Code
27104
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D'Angelo, Sandra P; Mahoney, Michelle R; Van Tine, Brian A et al. (2018) Nivolumab with or without ipilimumab treatment for metastatic sarcoma (Alliance A091401): two open-label, non-comparative, randomised, phase 2 trials. Lancet Oncol 19:416-426
Cheng, Heather H; Plets, Melissa; Li, Hongli et al. (2018) Circulating microRNAs and treatment response in the Phase II SWOG S0925 study for patients with new metastatic hormone-sensitive prostate cancer. Prostate 78:121-127
Li, Megan; Mulkey, Flora; Jiang, Chen et al. (2018) Identification of a Genomic Region between SLC29A1 and HSP90AB1 Associated with Risk of Bevacizumab-Induced Hypertension: CALGB 80405 (Alliance). Clin Cancer Res 24:4734-4744
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Uy, Geoffrey L; Mandrekar, Sumithra J; Laumann, Kristina et al. (2017) A phase 2 study incorporating sorafenib into the chemotherapy for older adults with FLT3-mutated acute myeloid leukemia: CALGB 11001. Blood Adv 1:331-340
Ou, Sai-Hong Ignatius; Moon, James; Garland, Linda L et al. (2015) SWOG S0722: phase II study of mTOR inhibitor everolimus (RAD001) in advanced malignant pleural mesothelioma (MPM). J Thorac Oncol 10:387-91
Budd, George T; Barlow, William E; Moore, Halle C F et al. (2015) SWOG S0221: a phase III trial comparing chemotherapy schedules in high-risk early-stage breast cancer. J Clin Oncol 33:58-64
Voorhees, Peter M; Orlowski, Robert Z; Mulkey, Flora et al. (2015) Long-term outcomes for newly-diagnosed multiple myeloma patients treated with pegylated liposomal doxorubicin and bortezomib: final results of CALGB (Alliance) 10301, a multicentre phase II study. Br J Haematol 171:373-7

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