This is an application for cancer research as a Member Institution of the Southwest Oncology Group.
The specific aims are 1) to conduct single and multidisciplinary clinical trials as described in Group protocols, 2) to conduct institutional pilot studies to propose for future Group trials, 3) to continue to expand CGOP affiliations, 4) to educate physicians, nurses, fellows, house officers, and allied health professionals as to the methods and procedures involved in the conduct of clinical trials, 5) to participate in the administrative and scientific activities of the Group, 6) to maintain a data management system which will provide timely highly quality research related data to the statistical office of the Southwest Oncology Group, and 7)recruit woman and patients from minority groups into cancer clinical trials. Disciplines within the institution which will participate in this work include: Medical Oncology, Hematology, Radiation Oncology, surgical Oncology, Pathology, Thoracic Surgery, Medical Genetics, Otolaryngology, Dermatology, and Urology. This work will be accomplished through the efforts of our highly trained team of data managers and research nurses under the direction of the Principal Investigator. This group of individuals works directly with each of our COOP affiliates in order to assist them in meeting their accrual goals, they play a essential role in reviewing eligibility criteria for candidates for clinical trials and continuously monitor the management of each patient enrolled in therapeutic trials in assure their evaluability.
|Messing, Edward M; Tangen, Catherine M; Lerner, Seth P et al. (2018) Effect of Intravesical Instillation of Gemcitabine vs Saline Immediately Following Resection of Suspected Low-Grade Non-Muscle-Invasive Bladder Cancer on Tumor Recurrence: SWOG S0337 Randomized Clinical Trial. JAMA 319:1880-1888|
|West, Howard L; Moon, James; Wozniak, Antoinette J et al. (2018) Paired Phase II Studies of Erlotinib/Bevacizumab for Advanced Bronchioloalveolar Carcinoma or Never Smokers With Advanced Non-Small-cell Lung Cancer: SWOG S0635 and S0636 Trials. Clin Lung Cancer 19:84-92|
|Cheng, Heather H; Plets, Melissa; Li, Hongli et al. (2018) Circulating microRNAs and treatment response in the Phase II SWOG S0925 study for patients with new metastatic hormone-sensitive prostate cancer. Prostate 78:121-127|
|Samlowski, Wolfram E; Moon, James; Witter, Merle et al. (2017) High frequency of brain metastases after adjuvant therapy for high-risk melanoma. Cancer Med 6:2576-2585|
|Heinrich, Michael C; Rankin, Cathryn; Blanke, Charles D et al. (2017) Correlation of Long-term Results of Imatinib in Advanced Gastrointestinal Stromal Tumors With Next-Generation Sequencing Results: Analysis of Phase 3 SWOG Intergroup Trial S0033. JAMA Oncol 3:944-952|
|Goldkorn, Amir; Ely, Benjamin; Tangen, Catherine M et al. (2015) Circulating tumor cell telomerase activity as a prognostic marker for overall survival in SWOG 0421: a phase III metastatic castration resistant prostate cancer trial. Int J Cancer 136:1856-62|
|Yu, Evan Y; Li, Hongli; Higano, Celestia S et al. (2015) SWOG S0925: A Randomized Phase II Study of Androgen Deprivation Combined With Cixutumumab Versus Androgen Deprivation Alone in Patients With New Metastatic Hormone-Sensitive Prostate Cancer. J Clin Oncol 33:1601-8|
|Othus, Megan; Appelbaum, Frederick R; Petersdorf, Stephen H et al. (2015) Fate of patients with newly diagnosed acute myeloid leukemia who fail primary induction therapy. Biol Blood Marrow Transplant 21:559-64|
|Budd, George T; Barlow, William E; Moore, Halle C F et al. (2015) SWOG S0221: a phase III trial comparing chemotherapy schedules in high-risk early-stage breast cancer. J Clin Oncol 33:58-64|
|Gralow, Julie R; Barlow, William E; Lew, Danika et al. (2014) A phase II study of docetaxel and vinorelbine plus filgrastim for HER-2 negative, stage IV breast cancer: SWOG S0102. Breast Cancer Res Treat 143:351-8|
Showing the most recent 10 out of 139 publications