The Scottsdale Community Clinical Oncology Program (CCOP) proposal involves a multidisciplinary group of physicians and other medical professionals dedicated to continue high quality clinical cancer treatment, cancer prevention, and cancer control research. This application responds to a continued need to bring these benefits of the National Cancer Program to a substantial population in Scottsdale and its regional referral area. Participants have demonstrated significant achievements in clinical cancer research, public education, and professional medical education. Scottsdale has a well-established and productive relationship with its primary research base, the North Central Cancer Treatment Group (NCCTG). Since 1987, the Scottsdale medical community has generated clinical cancer research data of excellent quality by placing large numbers of patients on high-priority, nationally - approved, clinical cancer research protocols. Scottsdale research base affiliations also include the Eastern Cooperative Oncology Group (ECOG), the Radiation Therapy Oncology Group (RTOG), and Mayo Clinic. Our specific objectives include the further development of available cancer prevention, cancer treatment, and cancer control research protocols to patients in Scottsdale, other areas in the state of Arizona, western New Mexico, southern Utah, southeastern California, southeastern Nevada, southwestern Colorado, and the greater Phoenix area. This project will continue to speed the transfer of newly developed cancer intervention technology to reduce regional cancer morbidity and mortality through widespread community applications. We have the ability to continue participation in specific cancer prevention and control protocols in view of our demonstrated professional discipline and established access to a substantial local and regional referral patient population base. Through community-based volunteer organizations and activities, public education and professional education, the Scottsdale CCOP will increase the number of patients involved in cancer prevention and control research studies. Cancer prevention and control research protocol participation will be further facilitated by local and regional primary health care providers. Scottsdale deserves a CCOP award by virtue of its record of proven past performance in clinical cancer research protocols, and its potential for increasing local and regional cancer prevention and control research. We confidently predict that Scottsdale will enter more than 100 patients on clinical cancer treatment research protocols and more than 50 patients on clinical cancer prevention and control protocols during the first year of the grant award.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10CA060276-02
Application #
2100998
Study Section
Special Emphasis Panel (SRC (70))
Project Start
1993-09-30
Project End
1996-05-31
Budget Start
1994-06-01
Budget End
1995-05-31
Support Year
2
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Mayo Clinic, Arizona
Department
Type
DUNS #
City
Scottsdale
State
AZ
Country
United States
Zip Code
85259
Schild, Steven E; Hillman, Shauna L; Tan, Angelina D et al. (2017) Long-Term Results of a Trial of Concurrent Chemotherapy and Escalating Doses of Radiation for Unresectable Non-Small Cell Lung Cancer: NCCTG N0028 (Alliance). J Thorac Oncol 12:697-703
Crozier, Jennifer A; Advani, Pooja P; LaPlant, Betsy et al. (2016) N0436 (Alliance): A Phase II Trial of Irinotecan With Cetuximab in Patients With Metastatic Breast Cancer Previously Exposed to Anthracycline and/or Taxane-Containing Therapy. Clin Breast Cancer 16:23-30
Kottschade, Lisa A; Suman, Vera J; Perez, Domingo G et al. (2013) A randomized phase 2 study of temozolomide and bevacizumab or nab-paclitaxel, carboplatin, and bevacizumab in patients with unresectable stage IV melanoma : a North Central Cancer Treatment Group study, N0775. Cancer 119:586-92
Atherton, Pamela J; Halyard, Michele Y; Sloan, Jeff A et al. (2013) Assessment of patient-reported measures of bowel function before and after pelvic radiotherapy: an ancillary study of the North Central Cancer Treatment Group study N00CA. Support Care Cancer 21:1193-9
Barton, Debra L; Liu, Heshan; Dakhil, Shaker R et al. (2013) Wisconsin Ginseng (Panax quinquefolius) to improve cancer-related fatigue: a randomized, double-blind trial, N07C2. J Natl Cancer Inst 105:1230-8
Galanis, Evanthia; Anderson, S Keith; Lafky, Jackie M et al. (2013) Phase II study of bevacizumab in combination with sorafenib in recurrent glioblastoma (N0776): a north central cancer treatment group trial. Clin Cancer Res 19:4816-23
Bolton, John S; O'Connell, Michael J; Mahoney, Michelle R et al. (2012) Hepatic arterial infusion and systemic chemotherapy after multiple metastasectomy in patients with colorectal carcinoma metastatic to the liver: a North Central Cancer Treatment Group (NCCTG) phase II study, 92-46-52. Clin Colorectal Cancer 11:31-7
Laack, Nadia N; O'Neill, Brian Patrick; Ballman, Karla V et al. (2011) CHOD/BVAM chemotherapy and whole-brain radiotherapy for newly diagnosed primary central nervous system lymphoma. Int J Radiat Oncol Biol Phys 81:476-82
Barton, Debra L; Soori, Gamini S; Bauer, Brent A et al. (2010) Pilot study of Panax quinquefolius (American ginseng) to improve cancer-related fatigue: a randomized, double-blind, dose-finding evaluation: NCCTG trial N03CA. Support Care Cancer 18:179-87
Moraska, Amanda R; Atherton, Pamela J; Szydlo, Daniel W et al. (2010) Gabapentin for the management of hot flashes in prostate cancer survivors: a longitudinal continuation Study-NCCTG Trial N00CB. J Support Oncol 8:128-32

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