Northwestern University has participated in the NICHD Maternal Fetal Medicine Units Network for the last two cycles, and is applying to continue this participation through 2016. There are no substantial changes to the organization of our Center, with the principal investigator, both alternate principal investigators, and the research coordinator unchanged. Botii sites for our Center continue to have expanding clinical volume, making it one of the largest obstetric volume centers in the Network. We have a proven record of collaboration in clinical research both outside and within the Network. Our contributions over the last cycle have included not only high recruitment and data quality rankings, but also major contributions in protocol submissions and trial management.

Public Health Relevance

Despite significant efforts over the past two decades, rates of premature birth in the US have not decreased and remain major causes of perinatal morbidity. The MFMU Network will cooperate to perform research to identify optimal management strategies in this area, as well as in the area of medical complications of pregnancy. We have participated in trials such as the 17-P trial and the BEAM trial which have made major impacts on our field, and we look forward to the opportunity to continue with our contributions.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Cooperative Clinical Research--Cooperative Agreements (U10)
Project #
5U10HD040512-15
Application #
8638044
Study Section
Special Emphasis Panel (ZHD1-DRG-D (50))
Program Officer
Ilekis, John V
Project Start
2001-04-01
Project End
2016-03-31
Budget Start
2014-04-01
Budget End
2015-03-31
Support Year
15
Fiscal Year
2014
Total Cost
$292,145
Indirect Cost
$86,999
Name
Northwestern University at Chicago
Department
Obstetrics & Gynecology
Type
Schools of Medicine
DUNS #
005436803
City
Chicago
State
IL
Country
United States
Zip Code
60611
Grobman, William A; Rice, Madeline M; Reddy, Uma M et al. (2018) Labor Induction versus Expectant Management in Low-Risk Nulliparous Women. N Engl J Med 379:513-523
Tita, Alan T N; Jablonski, Kathleen A; Bailit, Jennifer L et al. (2018) Neonatal outcomes of elective early-term births after demonstrated fetal lung maturity. Am J Obstet Gynecol 219:296.e1-296.e8
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Grobman, William A; Bailit, Jennifer; Lai, Yinglei et al. (2018) Defining failed induction of labor. Am J Obstet Gynecol 218:122.e1-122.e8
Kominiarek, Michelle A; Smid, Marcela C; Mele, Lisa et al. (2018) Child Neurodevelopmental Outcomes by Prepregnancy Body Mass Index and Gestational Weight Gain. Obstet Gynecol 132:1386-1393
Varner, Michael W; Mele, Lisa; Casey, Brian M et al. (2018) Thyroid function in neonates of women with subclinical hypothyroidism or hypothyroxinemia. J Perinatol 38:1490-1495
Randis, Tara M; Rice, Madeline Murguia; Myatt, Leslie et al. (2018) Incidence of early-onset sepsis in infants born to women with clinical chorioamnionitis. J Perinat Med 46:926-933

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