Northwestern University has participated in the NICHD Maternal Fetal Medicine Units Network for the last two cycles, and is applying to continue this participation through 2016. There are no substantial changes to the organization of our Center, with the principal investigator, both alternate principal investigators, and the research coordinator unchanged. Botii sites for our Center continue to have expanding clinical volume, making it one of the largest obstetric volume centers in the Network. We have a proven record of collaboration in clinical research both outside and within the Network. Our contributions over the last cycle have included not only high recruitment and data quality rankings, but also major contributions in protocol submissions and trial management.
Despite significant efforts over the past two decades, rates of premature birth in the US have not decreased and remain major causes of perinatal morbidity. The MFMU Network will cooperate to perform research to identify optimal management strategies in this area, as well as in the area of medical complications of pregnancy. We have participated in trials such as the 17-P trial and the BEAM trial which have made major impacts on our field, and we look forward to the opportunity to continue with our contributions.
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|Clark, Erin A S; Weiner, Steven J; Rouse, Dwight J et al. (2018) Genetic Variation, Magnesium Sulfate Exposure, and Adverse Neurodevelopmental Outcomes Following Preterm Birth. Am J Perinatol 35:1012-1022|
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|Grobman, William A; Rice, Madeline M; Reddy, Uma M et al. (2018) Labor Induction versus Expectant Management in Low-Risk Nulliparous Women. N Engl J Med 379:513-523|
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|Grobman, William A; Bailit, Jennifer; Sandoval, Grecio et al. (2018) The Association of Decision-to-Incision Time for Cesarean Delivery with Maternal and Neonatal Outcomes. Am J Perinatol 35:247-253|
|Saade, G R; Thom, E A; Grobman, W A et al. (2018) Cervical funneling or intra-amniotic debris and preterm birth in nulliparous women with midtrimester cervical length less than 30 mm. Ultrasound Obstet Gynecol 52:757-762|
|Chauhan, Suneet P; Weiner, Steven J; Saade, George R et al. (2018) Intrapartum Fetal Heart Rate Tracing Among Small-for-Gestational Age Compared With Appropriate-for-Gestational-Age Neonates. Obstet Gynecol 132:1019-1025|
|Kominiarek, Michelle A; Saade, George; Mele, Lisa et al. (2018) Association Between Gestational Weight Gain and Perinatal Outcomes. Obstet Gynecol 132:875-881|
|Grobman, William A; Bailit, Jennifer; Lai, Yinglei et al. (2018) Defining failed induction of labor. Am J Obstet Gynecol 218:122.e1-122.e8|
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