Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI031599-06
Application #
2003705
Study Section
Special Emphasis Panel (SRC (34))
Project Start
1991-09-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Ohta, Shin; Imamura, Mitsuru; Xing, Wei et al. (2013) Group V secretory phospholipase A2 is involved in macrophage activation and is sufficient for macrophage effector functions in allergic pulmonary inflammation. J Immunol 190:5927-38
Lundequist, Anders; Boyce, Joshua A (2011) LPA5 is abundantly expressed by human mast cells and important for lysophosphatidic acid induced MIP-1? release. PLoS One 6:e18192
Saino, Hiromichi; Ukita, Yoko; Ago, Hideo et al. (2011) The catalytic architecture of leukotriene C4 synthase with two arginine residues. J Biol Chem 286:16392-401
Laidlaw, Tanya M; Steinke, John W; Tinana, Adrienne M et al. (2011) Characterization of a novel human mast cell line that responds to stem cell factor and expresses functional FcýýRI. J Allergy Clin Immunol 127:815-22.e1-5
Giannattasio, Giorgio; Ohta, Shin; Boyce, Joshua R et al. (2011) The purinergic G protein-coupled receptor 6 inhibits effector T cell activation in allergic pulmonary inflammation. J Immunol 187:1486-95
Giannattasio, Giorgio; Fujioka, Daisuke; Xing, Wei et al. (2010) Group V secretory phospholipase A2 reveals its role in house dust mite-induced allergic pulmonary inflammation by regulation of dendritic cell function. J Immunol 185:4430-8
Lundequist, Anders; Nallamshetty, Samridhi N; Xing, Wei et al. (2010) Prostaglandin E(2) exerts homeostatic regulation of pulmonary vascular remodeling in allergic airway inflammation. J Immunol 184:433-41
Barrett, Nora A; Maekawa, Akiko; Rahman, Opu M et al. (2009) Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells. J Immunol 182:1119-28
Jones, Tatiana G; Hallgren, Jenny; Humbles, Alison et al. (2009) Antigen-induced increases in pulmonary mast cell progenitor numbers depend on IL-9 and CD1d-restricted NKT cells. J Immunol 183:5251-60
Jiang, Yongfeng; Borrelli, Laura; Bacskai, Brian J et al. (2009) P2Y6 receptors require an intact cysteinyl leukotriene synthetic and signaling system to induce survival and activation of mast cells. J Immunol 182:1129-37

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