Abstract

This ICIDR is concerned with advancing knowledge of the complex interactions between the host, vector, and parasite that underlie the pathogenesis of bancroftian filariasis. It also has the practical goal of applying this quantitative information to assessment and development of control strategies aimed at controlling filariasis. As such, a major task will be to maintain accurate databases that are accessible to each of the Projects.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
2U19AI033061-06
Application #
6229783
Study Section
Special Emphasis Panel (ZAI1-MSQ-M (M1))
Project Start
1999-09-30
Project End
2004-02-28
Budget Start
Budget End
Support Year
6
Fiscal Year
1999
Total Cost
Indirect Cost

  Institution

Name
Case Western Reserve University
Department
Type
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106

  Publications

Nayakwadi Singer, Monica; Heath, Claire; Muinde, Jackson et al. (2017) Pneumococcal Vaccine Response After Exposure to Parasites in Utero, in Infancy, or Mid-Childhood. Pediatrics 139:
Pedraza-Sánchez, Sigifredo; Hise, Amy G; Ramachandra, Lakshmi et al. (2013) Reduced frequency of a CD14+ CD16+ monocyte subset with high Toll-like receptor 4 expression in cord blood compared to adult blood contributes to lipopolysaccharide hyporesponsiveness in newborns. Clin Vaccine Immunol 20:962-71
Bowman, Natalie M; Kawai, Vivian; Gilman, Robert H et al. (2011) Autonomic dysfunction and risk factors associated with Trypanosoma cruzi infection among children in Arequipa, Peru. Am J Trop Med Hyg 84:85-90
Levy, Michael Z; Bowman, Natalie M; Kawai, Vivian et al. (2009) Spatial patterns in discordant diagnostic test results for Chagas disease: links to transmission hotspots. Clin Infect Dis 48:1104-6
Rao, Ramakrishna U; Huang, Yuefang; Bockarie, Moses J et al. (2009) A qPCR-based multiplex assay for the detection of Wuchereria bancrofti, Plasmodium falciparum and Plasmodium vivax DNA. Trans R Soc Trop Med Hyg 103:365-70
Michael, Edwin; Snow, Lucy C; Bockarie, Moses J (2009) Ecological meta-analysis of density-dependent processes in the transmission of lymphatic filariasis: survival of infected vectors. J Med Entomol 46:873-80
Bockarie, Moses J; Pedersen, Erling M; White, Graham B et al. (2009) Role of vector control in the global program to eliminate lymphatic filariasis. Annu Rev Entomol 54:469-87
Michael, Edwin; Malecela, Mwele N; Zervos, Mihail et al. (2008) Global eradication of lymphatic filariasis: the value of chronic disease control in parasite elimination programmes. PLoS One 3:e2936
Levy, Michael Z; Quispe-Machaca, Victor R; Ylla-Velasquez, Jose L et al. (2008) Impregnated netting slows infestation by Triatoma infestans. Am J Trop Med Hyg 79:528-34
Bowman, Natalie M; Kawai, Vivian; Levy, Michael Z et al. (2008) Chagas disease transmission in periurban communities of Arequipa, Peru. Clin Infect Dis 46:1822-8

Showing the most recent 10 out of 15 publications