Abstract

The purpose of the Clinical Core is to provide biological specimens and behavioral data to all of the individual research projects. This core will be located in Indianapolis. Core research personnel will enroll and maintain the cohort of middle adolescent female research subjects over the five year duration of the center, collect all required biological samples (genitourinary swabs, endocervical secretions, vaginal lavages, urine, cervical biopsies, and blood), behavioral information (self-administered questionnaires and personal interviews), and provide interim reproductive health examinations and data collection to facilitate subject retention. Research personnel will include research coordinator, research nurse practitioner, and two Disease Intervention Specialists (DIS) from the Marion Country Health Department. The research nurse will obtain all biological specimens. DIS will perform two important fieldwork functions: (1) contact sexual partners of subjects to obtained personal information, urine samples, provide appropriate antibiotic treatment when partners of infected women prefer to be treated outside of the Marion County STD Clinic (Bell Flower); (2) weekly contact with all subjects during the three month period of intense data collection to obtain urine samples and self-directed vaginal swabs, personal behavioral diaries and interview information.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
1U19AI043924-01
Application #
6100286
Study Section
Project Start
1998-09-30
Project End
1999-08-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
1
Fiscal Year
1998
Total Cost
Indirect Cost

  Institution

Name
Indiana University-Purdue University at Indianapolis
Department
Type
DUNS #
005436803
City
Indianapolis
State
IN
Country
United States
Zip Code
46202

  Publications

Hensel, Devon J; Sorge, Brandon H (2014) Adolescent women's daily academic behaviors, sexual behaviors, and sexually related emotions. J Adolesc Health 55:845-7
Tanner, Amanda E; Roof, Katherine A; Katz, Barry P et al. (2012) A comparison of young women's actual and assigned timing of use of a microbicide surrogate. Sex Health 9:299-303
Hensel, Devon J; Fortenberry, J Dennis (2011) Adolescent mothers' sexual, contraceptive, and emotional relationship content with the fathers of their children following a first diagnosis of sexually transmitted infection. J Adolesc Health 49:327-9
Batteiger, Byron E; Tu, Wanzhu; Ofner, Susan et al. (2010) Repeated Chlamydia trachomatis genital infections in adolescent women. J Infect Dis 201:42-51
Barousse, Melissa M; Theall, Katherine P; Van Der Pol, Barbara et al. (2007) Susceptibility of middle adolescent females to sexually transmitted infections: impact of hormone contraception and sexual behaviors on vaginal immunity. Am J Reprod Immunol 58:159-68
Woodrome, Stacey E; Zimet, Gregory D; Orr, Donald P et al. (2006) Dyadic alcohol use and relationship quality as predictors of condom non-use among adolescent females. J Adolesc Health 38:305-6
Shew, Marcia L; Fortenberry, J Dennis; Tu, Wanzhu et al. (2006) Association of condom use, sexual behaviors, and sexually transmitted infections with the duration of genital human papillomavirus infection among adolescent women. Arch Pediatr Adolesc Med 160:151-6
Aalsma, Matthew C; Fortenberry, J Dennis; Sayegh, M Aaron et al. (2006) Family and friend closeness to adolescent sexual partners in relationship to condom use. J Adolesc Health 38:173-8
Wu, Hsing-Ju; Seib, Kate L; Srikhanta, Yogitha N et al. (2006) PerR controls Mn-dependent resistance to oxidative stress in Neisseria gonorrhoeae. Mol Microbiol 60:401-16
Blythe, Margaret J; Fortenberry, J Dennis; Temkit, M'Hamed et al. (2006) Incidence and correlates of unwanted sex in relationships of middle and late adolescent women. Arch Pediatr Adolesc Med 160:591-5

Showing the most recent 10 out of 33 publications