The objective of this core is to provide diagnostic services, patient specimens and clinical data in support of each of the projects. The core will be comprised of the director, the laboratory manager, and one technician. At each patient encounter, various specimens will be collected and transported to the laboratory. Each specimen will be aliquoted for diagnostic testing and for distribution to appropriate investigators. Samples to be collected include urine, blood, vaginal lavage, saliva and a self-collected vaginal swab. Not all samples will be collected at each visit. Diagnostic assays that will be performed include ligase chain reaction (LCR) on the urine samples for the detection of C. trachomatis and N. gonorrhea, trichomonas cultures on self-collected vaginal swabs; and chlamydial serologies on sera. Urine will also be aliquoted and stored to provide material for sequencing of the chlamydial omp1 gene as part of Project 2 (Batteiger). In addition to diagnostic serology, blood collected will be used to isolate lymphocytes for T-cell proliferation assays in support of Project 3 (Fidel). The vaginal lavage samples will be collected for Project 3 and shipped in accordance with Dr. Fidel's specifications. Gonorrhea isolates will be collected and stored for batch shipment to Dr. Apicella (Project 5).

Project Start
2000-09-01
Project End
2001-08-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
3
Fiscal Year
2000
Total Cost
$138,502
Indirect Cost
Name
Indiana University-Purdue University at Indianapolis
Department
Type
DUNS #
005436803
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Hensel, Devon J; Sorge, Brandon H (2014) Adolescent women's daily academic behaviors, sexual behaviors, and sexually related emotions. J Adolesc Health 55:845-7
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Hensel, Devon J; Fortenberry, J Dennis (2011) Adolescent mothers' sexual, contraceptive, and emotional relationship content with the fathers of their children following a first diagnosis of sexually transmitted infection. J Adolesc Health 49:327-9
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Aalsma, Matthew C; Fortenberry, J Dennis; Sayegh, M Aaron et al. (2006) Family and friend closeness to adolescent sexual partners in relationship to condom use. J Adolesc Health 38:173-8
Wu, Hsing-Ju; Seib, Kate L; Srikhanta, Yogitha N et al. (2006) PerR controls Mn-dependent resistance to oxidative stress in Neisseria gonorrhoeae. Mol Microbiol 60:401-16
Blythe, Margaret J; Fortenberry, J Dennis; Temkit, M'Hamed et al. (2006) Incidence and correlates of unwanted sex in relationships of middle and late adolescent women. Arch Pediatr Adolesc Med 160:591-5

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