The overall goal of Core C-Molecular Biology is to provide research, training and collaborative support for Projects 1, 2, and 3 of the ICIDR African Malaria Vectors. Core C currently exists as the ICIPE Department of Molecular Biology and Biotechnology (MBB). The Head of the Department, Dr. Ellie O. Osir, will also serve as the Core Leader. Core C has 3 specific aims: 1) to provide molecular biology research support for the 3 ICIDR projects: Larval Ecology, Behavior, and Vector Competence, 2) to provide training support for ICIDR team members and visiting national and international collaborators, and 3) to provide linkages with an international network of insect molecular biologists and to assist with publication of papers and presentations of research results. Some of the technical inputs that Core C will provide include PCR identification of Anopheles gambiae complex, the use of random amplified polymorphic DNA-PCR and microsatellite markers for studying the population genetics of Anopheles gambiae complex, QTL mapping if malaria-refractory genes in mosquitoes. Core C resources will be divided according to: 40% Project 1- Larval Ecology, 20% Project 2- Behavior, and 40% Project 3-Vector Competence. The Core Leader and staff of the MBB Department have extensive international linkages to well-recognized insect molecular biologists and physiologists. Many of these notable insect biologists are already helping ICIPE/MBB with other programs at the Nairobi laboratories. This ICIDR project will benefit from these professional contacts and we anticipate that this will have a major impact on the quality of the science.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
3U19AI045511-02S1
Application #
6442915
Study Section
Special Emphasis Panel (ZAI1)
Project Start
2001-04-01
Project End
2001-08-31
Budget Start
Budget End
Support Year
2
Fiscal Year
2001
Total Cost
$159,181
Indirect Cost
Name
Tulane University
Department
Type
DUNS #
City
New Orleans
State
LA
Country
United States
Zip Code
70118
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Impoinvil, Daniel E; Mbogo, Charles M; Keating, Joseph et al. (2008) The role of unused swimming pools as a habitat for Anopheles immature stages in urban Malindi, Kenya. J Am Mosq Control Assoc 24:457-9
Mireji, Paul O; Keating, Joseph; Hassanali, Ahmed et al. (2008) Heavy metals in mosquito larval habitats in urban Kisumu and Malindi, Kenya, and their impact. Ecotoxicol Environ Saf 70:147-53
Mwangangi, Joseph M; Mbogo, Charles M; Muturi, Ephantus J et al. (2007) Spatial distribution and habitat characterisation of Anopheles larvae along the Kenyan coast. J Vector Borne Dis 44:44-51

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