Objectives The objective of this Core C is to develop and implement comprehensive training programs in HIM management and the conduct of clinical research protocols for health professionals in Thailand and Cambodia.
Specific aims 1. to establish a faculty of trainers with expertise in adult HIM care, pediatric HIM care and the conduct of clinical trials 2. to recruit and train new investigators, nurses and laboratory scientists for careers in clinical research 3. to provide initial and ongoing training in the conduct of clinical trials to the international standards of Good Clinical Practice (GCP) and Good Laboratory Practice (GLP) for study sites participating in this CIPRA program 4. to provide project-specific training for site investigators, nurses and laboratory staff 5. to establish and maintain a Thailand/Cambodia CIPRA website for information dissemination and exchange 6. to employ a clinical research assistant (CRA) 7. to employ a nurse team leader/educator dedicated to this CIPRA program 8. to utililise existing senior HIV-NAT personnel as trainers 9. to produce training materials Methods The trainers will use existing training resources and material at HIM-NAT which cover GCP, HIM medicine, clinical trial conduct and laboratory techniques. These training resources will be adapted to the needs of the CIPRA projects and to the needs of the two participating countries. The faculty will be directed by the CIPRA Program Co-ordinator, Dr Chris Duncombe and supervised by the Core Leader, Theshinee Chuenyam. The Core Leader will recruit and train new personnel, including a CRA who will work with CIPRA personnel to develop training materials and implement GCP/GLP training according to the needs of the sites. This person will also supervise the monitoring of the studies. The existing laboratory manager, Sasiwimol Ubolyam, will supervise GLP training. Experience in GCP/GLP and HIM clinical management will vary between the sites. Some sites will have conducted clinical trials in the past and some, such as primary and secondary care hospitals in Thailand and the sites in Cambodia, will be participating in clinical trials for the first time. Two separate comprehensive training plans are presented, one for Thailand and one for Cambodia.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI053741-07
Application #
8114104
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2010-06-01
Budget End
2011-05-31
Support Year
7
Fiscal Year
2010
Total Cost
$25,492
Indirect Cost
Name
HIV-Nat, the Thai Red Cross AIDS Rch Center
Department
Type
DUNS #
671556129
City
Bangkok
State
Country
Thailand
Zip Code
10330
Paul, Robert; Apornpong, Tanakorn; Prasitsuebsai, Wasana et al. (2018) Cognition, Emotional Health, and Immunological Markers in Children With Long-Term Nonprogressive HIV. J Acquir Immune Defic Syndr 77:417-426
Paul, Robert; Prasitsuebsai, Wasana; Jahanshad, Neda et al. (2018) Structural Neuroimaging and Neuropsychologic Signatures in Children With Vertically Acquired HIV. Pediatr Infect Dis J 37:662-668
Bunupuradah, Torsak; Hansudewechakul, Rawiwan; Kosalaraksa, Pope et al. (2015) HLA-DRB1454 and predictors of new-onset asthma in HIV-infected Thai children. Clin Immunol 157:26-9
Ananworanich, Jintanat; Kerr, Stephen J; Jaimulwong, Tanyathip et al. (2015) Soluble CD163 and monocyte populations in response to antiretroviral therapy and in relationship with neuropsychological testing among HIV-infected children. J Virus Erad 1:196-202
Kerr, Stephen J; Puthanakit, Thanyawee; Vibol, Ung et al. (2014) Neurodevelopmental outcomes in HIV-exposed-uninfected children versus those not exposed to HIV. AIDS Care 26:1327-35
Intasan, Jintana; Bunupuradah, Torsak; Vonthanak, Saphonn et al. (2014) Comparison of adherence monitoring tools and correlation to virologic failure in a pediatric HIV clinical trial. AIDS Patient Care STDS 28:296-302
Puthanakit, Thanyawee; Ananworanich, Jintanat; Vonthanak, Saphonn et al. (2013) Cognitive function and neurodevelopmental outcomes in HIV-infected Children older than 1 year of age randomized to early versus deferred antiretroviral therapy: the PREDICT neurodevelopmental study. Pediatr Infect Dis J 32:501-8
Bunupuradah, Torsak; Kosalaraksa, Pope; Vibol, Ung et al. (2013) Impact of antiretroviral therapy on quality of life in HIV-infected Southeast Asian children in the PREDICT study. AIDS Patient Care STDS 27:596-603
Bunupuradah, T; Ubolyam, S; Hansudewechakul, R et al. (2012) Correlation of selenium and zinc levels to antiretroviral treatment outcomes in Thai HIV-infected children without severe HIV symptoms. Eur J Clin Nutr 66:900-5
Puthanakit, Thanyawee; Saphonn, Vonthanak; Ananworanich, Jintanat et al. (2012) Early versus deferred antiretroviral therapy for children older than 1 year infected with HIV (PREDICT): a multicentre, randomised, open-label trial. Lancet Infect Dis 12:933-41

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