Abstract

The Pilot Project component presents interested investigators with the opportunity to explore innovative and novel research questions centered on human immunology and category A-C pathogens. In such a way, the component allows for the possibility of the stimulation of new areas of interest for the Technological Development Component and the production of cutting edge human immunology and Biodefense research projects while encouraging the development of translational research skills and experience. The Component will function to: 1) support promising small scale novel and innovative human immunological research projects that utilize or develop the Center's technology and possess the potential of developing into R21 or R01 scale projects and 2) encourage junior or clinically oriented investigators to develop translational research skills and experience in the area of human immunology research. Included in this application are )ossible pilot projects eligible for receiving funding under CIVIA's pilot project criteria.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI062623-05
Application #
7677392
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2008-09-01
Budget End
2009-08-31
Support Year
5
Fiscal Year
2008
Total Cost
$361,147
Indirect Cost

  Institution

Name
Icahn School of Medicine at Mount Sinai
Department
Type
DUNS #
078861598
City
New York
State
NY
Country
United States
Zip Code
10029

  Publications

Stein, Cheryl R; Ge, Yongchao; Wolff, Mary S et al. (2016) Perfluoroalkyl substance serum concentrations and immune response to FluMist vaccination among healthy adults. Environ Res 149:171-178
Barría, Maria Ines; Garrido, Jose Luis; Stein, Cheryl et al. (2013) Localized mucosal response to intranasal live attenuated influenza vaccine in adults. J Infect Dis 207:115-24
Seibert, Christopher W; Rahmat, Saad; Krammer, Florian et al. (2012) Efficient transmission of pandemic H1N1 influenza viruses with high-level oseltamivir resistance. J Virol 86:5386-9
Irie, Takashi; Liu, Yuliang; Drolet, Barbara S et al. (2012) Cytopathogenesis of vesicular stomatitis virus is regulated by the PSAP motif of M protein in a species-dependent manner. Viruses 4:1605-18
Pazos, Michael A; Kraus, Thomas A; Muñoz-Fontela, César et al. (2012) Estrogen mediates innate and adaptive immune alterations to influenza infection in pregnant mice. PLoS One 7:e40502
Irie, Takashi; Carnero, Elena; García-Sastre, Adolfo et al. (2012) In Vivo Replication and Pathogenesis of Vesicular Stomatitis Virus Recombinant M40 Containing Ebola Virus L-Domain Sequences. Infect Dis (Auckl) 5:59-64
Leung, Lawrence W; Park, Man-Seong; Martinez, Osvaldo et al. (2011) Ebolavirus VP35 suppresses IFN production from conventional but not plasmacytoid dendritic cells. Immunol Cell Biol 89:792-802
Baum, Alina; García-Sastre, Adolfo (2011) Differential recognition of viral RNA by RIG-I. Virulence 2:166-9
Baum, Alina; García-Sastre, Adolfo (2010) Induction of type I interferon by RNA viruses: cellular receptors and their substrates. Amino Acids 38:1283-99
Versteeg, Gijs A; Hale, Benjamin G; van Boheemen, Sander et al. (2010) Species-specific antagonism of host ISGylation by the influenza B virus NS1 protein. J Virol 84:5423-30

Showing the most recent 10 out of 105 publications