The Biostatistics Core will support data collection, entry, and analysis for Projects 1 and 2, and ensure that data are of high quality and that all data management and analysis procedures are compliant with international clinical trials standards, relevant U.S. regulations, and NIAID guidelines. Thus will be accomplished through close coordination between the CVD Senior Statistician, the MRTC Epidemiology and Biostatistics Unit, and DMID data management support contractors.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
1U19AI065683-01
Application #
6970513
Study Section
Special Emphasis Panel (ZAI1-GSM-M (M1))
Project Start
2005-07-01
Project End
2010-04-30
Budget Start
2005-07-01
Budget End
2006-04-30
Support Year
1
Fiscal Year
2005
Total Cost
$66,484
Indirect Cost
Name
University of Maryland Baltimore
Department
Type
DUNS #
188435911
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Graves, Shawna F; Kouriba, Bourema; Diarra, Issa et al. (2016) Strain-specific Plasmodium falciparum multifunctional CD4(+) T cell cytokine expression in Malian children immunized with the FMP2.1/AS02A vaccine candidate. Vaccine 34:2546-55
Malaria Genomic Epidemiology Network; Band, Gavin; Rockett, Kirk A et al. (2015) A novel locus of resistance to severe malaria in a region of ancient balancing selection. Nature 526:253-7
Travassos, Mark A; Coulibaly, Drissa; Bailey, Jason A et al. (2015) Differential recognition of terminal extracellular Plasmodium falciparum VAR2CSA domains by sera from multigravid, malaria-exposed Malian women. Am J Trop Med Hyg 92:1190-4
Gandhi, Kavita; Thera, Mahamadou A; Coulibaly, Drissa et al. (2014) Variation in the circumsporozoite protein of Plasmodium falciparum: vaccine development implications. PLoS One 9:e101783
Ouattara, Amed; Takala-Harrison, Shannon; Thera, Mahamadou A et al. (2013) Molecular basis of allele-specific efficacy of a blood-stage malaria vaccine: vaccine development implications. J Infect Dis 207:511-9
Travassos, Mark A; Niangaly, Amadou; Bailey, Jason A et al. (2013) Seroreactivity to Plasmodium falciparum erythrocyte membrane protein 1 intracellular domain in malaria-exposed children and adults. J Infect Dis 208:1514-9
Thera, Mahamadou A; Plowe, Christopher V (2012) Vaccines for malaria: how close are we? Annu Rev Med 63:345-57
Gandhi, Kavita; Thera, Mahamadou A; Coulibaly, Drissa et al. (2012) Next generation sequencing to detect variation in the Plasmodium falciparum circumsporozoite protein. Am J Trop Med Hyg 86:775-81
Thera, Mahamadou A; Doumbo, Ogobara K; Coulibaly, Drissa et al. (2011) A field trial to assess a blood-stage malaria vaccine. N Engl J Med 365:1004-13
Lyke, K E; Fernández-Vi?a, M A; Cao, K et al. (2011) Association of HLA alleles with Plasmodium falciparum severity in Malian children. Tissue Antigens 77:562-71

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