Abstract

Successful collaboration between the multiple sites for this Hepatitis C Center project will require dedicated administrative efforts to include: 1) facilitating communication and data sharing between the three project sites and the related personnel and Pis, 2) coordination of schedules for teleconferences and travel, 3) heavy email traffic and phone contact in regards to manuscript preparations, travel, sample transport etc., and 4) management and reporting of all project site budgets and related subcontracts.

Public Health Relevance

Successful collaborafive efforts of any size are greatly enhanced when administrative professional personnel effort is dedicated to the organization and execution of all related administrative duites.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI066328-09
Application #
8519234
Study Section
Special Emphasis Panel (ZAI1-BP-M)
Project Start
Project End
Budget Start
2013-09-01
Budget End
2014-08-31
Support Year
9
Fiscal Year
2013
Total Cost
$51,850
Indirect Cost
$9,599

  Institution

Name
University of Colorado Denver
Department
Type
DUNS #
041096314
City
Aurora
State
CO
Country
United States
Zip Code
80045

  Publications

Cobb, Dustin A; Kim, Ok-Kyung; Golden-Mason, Lucy et al. (2018) Hepatocyte-derived exosomes promote T follicular regulatory cell expansion during hepatitis C virus infection. Hepatology 67:71-85
Goh, Celeste C; Roggerson, Krystal M; Lee, Hai-Chon et al. (2016) Hepatitis C Virus-Induced Myeloid-Derived Suppressor Cells Suppress NK Cell IFN-? Production by Altering Cellular Metabolism via Arginase-1. J Immunol 196:2283-92
Narayanan, Sowmya; Surette, Fionna A; Hahn, Young S (2016) The Immune Landscape in Nonalcoholic Steatohepatitis. Immune Netw 16:147-58
Lim, Sung In; Hahn, Young S; Kwon, Inchan (2015) Site-specific albumination of a therapeutic protein with multi-subunit to prolong activity in vivo. J Control Release 207:93-100
Giugliano, Silvia; Kriss, Michael; Golden-Mason, Lucy et al. (2015) Hepatitis C virus infection induces autocrine interferon signaling by human liver endothelial cells and release of exosomes, which inhibits viral replication. Gastroenterology 148:392-402.e13
Golden-Mason, Lucy; Hahn, Young S; Strong, Michael et al. (2014) Extracellular HCV-core protein induces an immature regulatory phenotype in NK cells: implications for outcome of acute infection. PLoS One 9:e103219
Labonte, Adam C; Tosello-Trampont, Annie-Carole; Hahn, Young S (2014) The role of macrophage polarization in infectious and inflammatory diseases. Mol Cells 37:275-85
Brownell, Jessica; Bruckner, Jacob; Wagoner, Jessica et al. (2014) Direct, interferon-independent activation of the CXCL10 promoter by NF-?B and interferon regulatory factor 3 during hepatitis C virus infection. J Virol 88:1582-90
Lee, Hai-Chon; Narayanan, Sowmya; Park, Sung-Jae et al. (2014) Transcriptional regulation of IFN-? genes in hepatitis C virus-infected hepatocytes via IRF-3·IRF-7·NF-?B complex. J Biol Chem 289:5310-9
Stone, Amy E L; Mitchell, Angela; Brownell, Jessica et al. (2014) Hepatitis C virus core protein inhibits interferon production by a human plasmacytoid dendritic cell line and dysregulates interferon regulatory factor-7 and signal transducer and activator of transcription (STAT) 1 protein expression. PLoS One 9:e95627

Showing the most recent 10 out of 37 publications