The administrative and biostatistical core will manage the budgetary, administrative and statistical aspects of the Program Project Grant (Program). The Core will be responsible for coordinating meetings and interactions among investigators on the Program, transmitting data within the Program, communicating with NIAID program personnel, preparing publications and maintaining a bibliography describing work performed under the Program, and all financial matters relating to the Program. A statistician will provide expertise in analyzing the significance of our experimental data. An administrative manager will provide liaison with the hospital's financial office, office of research affairs, materials management, and will coordinate travel.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
1U19AI066705-01
Application #
7009887
Study Section
Special Emphasis Panel (ZAI1-PA-I (M1))
Project Start
2005-09-01
Project End
2010-06-30
Budget Start
2005-09-01
Budget End
2006-06-30
Support Year
1
Fiscal Year
2005
Total Cost
$111,117
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
073130411
City
Boston
State
MA
Country
United States
Zip Code
02199
Tonsho, M; Lee, S; Aoyama, A et al. (2015) Tolerance of Lung Allografts Achieved in Nonhuman Primates via Mixed Hematopoietic Chimerism. Am J Transplant 15:2231-9
Aoyama, A; Tonsho, M; Ng, C Y et al. (2015) Long-term lung transplantation in nonhuman primates. Am J Transplant 15:1415-20
Yamada, Yohei; Aoyama, Akihiro; Tocco, Georges et al. (2012) Differential effects of denileukin diftitox IL-2 immunotoxin on NK and regulatory T cells in nonhuman primates. J Immunol 188:6063-70
Millington, Timothy; Koulmanda, Maria; Ng, Choo et al. (2012) Effects of an agonist interleukin-2/Fc fusion protein, a mutant antagonist interleukin-15/Fc fusion protein, and sirolimus on cardiac allograft survival in non-human primates. J Heart Lung Transplant 31:427-35
Nadazdin, Ognjenka; Boskovic, Svjetlan; Wee, Siew-Lin et al. (2011) Contributions of direct and indirect alloresponses to chronic rejection of kidney allografts in nonhuman primates. J Immunol 187:4589-97
Nadazdin, Ognjenka; Boskovic, Svjetlan; Murakami, Toru et al. (2011) Host alloreactive memory T cells influence tolerance to kidney allografts in nonhuman primates. Sci Transl Med 3:86ra51
Benichou, Gilles; Yamada, Yohei; Aoyama, Akihiro et al. (2011) Natural killer cells in rejection and tolerance of solid organ allografts. Curr Opin Organ Transplant 16:47-53
Hanidziar, Dusan; Koulmanda, Maria; Strom, Terry B (2010) Creating transplant tolerance by taming adverse intragraft innate immunity. F1000 Biol Rep 2:83
Millington, Timothy M; Madsen, Joren C (2010) Innate immunity and cardiac allograft rejection. Kidney Int Suppl :S18-21
Nadazdin, Ognjenka; Boskovic, Svjetlan; Murakami, Toru et al. (2010) Phenotype, distribution and alloreactive properties of memory T cells from cynomolgus monkeys. Am J Transplant 10:1375-84

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