The Biostatistics Core will provide the personnel and knowledge needed for the most efficient utilization of the data collected by the investigators of this CMCR. Core investigators are committed to taking a direct interest in all quantitative issues arising in the proposed studies. They will participate in regular project and Center meetings and provide their input wherever statistical expertise is necessary. Statistical issues will be addressed at every level of every investigation from study design and data collection to the description and inferential statements made from the collected data. By contributing to diverse research projects, the core investigators will promote interdisciplinary interactions among various studies, thereby enhancing the synergistic effect of the Center. The core will offer a wide spectrum of services including data management, data analysis, development of new methodologies as needed, and computer simulations as may be required by a specific application. In addition, the Biostatistics Core will develop and test computer software to identify potentially important markers (cytokines) with good predictive qualities, out of a high dimensional array.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Research Program--Cooperative Agreements (U19)
Project #
Application #
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Rochester
United States
Zip Code
Zhang, Steven B; Yang, Shanmin; Zhang, Zhenhuan et al. (2017) Thoracic gamma irradiation-induced obesity in C57BL/6 female mice. Int J Radiat Biol 93:1334-1342
Groves, Angela M; Johnston, Carl J; Misra, Ravi S et al. (2015) Whole-Lung Irradiation Results in Pulmonary Macrophage Alterations that are Subpopulation and Strain Specific. Radiat Res 184:639-49
Zhang, Steven B; Yang, Shanmin; Vidyasagar, Sadasivan et al. (2015) PicoGreen assay of circular DNA for radiation biodosimetry. Radiat Res 183:188-95
Yang, Shanmin; Zhang, Mei; Chen, Chun et al. (2015) Triptolide Mitigates Radiation-Induced Pulmonary Fibrosis. Radiat Res 184:509-17
Yin, Liangjie; Vijaygopal, Pooja; Menon, Rejeesh et al. (2014) An amino acid mixture mitigates radiation-induced gastrointestinal toxicity. Health Phys 106:734-44
Johnston, Carl J; Manning, Casey M; Rangel-Moreno, Javier et al. (2013) Neonatal irradiation sensitizes mice to delayed pulmonary challenge. Radiat Res 179:475-84
Xiao, Zhenyu; Yang, Shanmin; Su, Ying et al. (2013) Alteration of the inflammatory molecule network after irradiation of soft tissue. Adv Exp Med Biol 765:335-341
Chen, Chun; Yang, Shanmin; Zhang, Mei et al. (2013) In vitro Sirius Red collagen assay measures the pattern shift from soluble to deposited collagen. Adv Exp Med Biol 765:47-53
Cherry, Jonathan D; Williams, Jacqueline P; O'Banion, M Kerry et al. (2013) Thermal injury lowers the threshold for radiation-induced neuroinflammation and cognitive dysfunction. Radiat Res 180:398-406
Ma, Jun; Hou, Yanqian; Han, Deping et al. (2013) Fibroblast growth factor-peptide promotes bone marrow recovery after irradiation. Adv Exp Med Biol 765:155-161

Showing the most recent 10 out of 77 publications