Abstract

The functions of the Training/Education Core are to: (1) provide CMCR members with appropriate training to help facilitate their research and maintain innovative and state-of-the-art approaches to address research questions, (2) provide training on radiation biology and epidemiology to increase understanding of the issues surrounding radiation exposure, and thereby further stimulate synergy between CMCR projects, (3) create a seminar series comprised of speakers invited from other research groups and institutions to present research results on topics in radiobiology, epidemiology, and medical countermeasures for CMCR members, University of Washington and Fred Hutchinson Cancer Research Center members, and others in the Seattle research community, (4) provide a resource for the lay community to help them understand risks associated with radiation exposure, and (5) create an External Scientific Advisory Committee to provide periodic reviews of each component of the CMCR.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI067770-02
Application #
7310432
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
2006-08-01
Budget End
2007-07-31
Support Year
2
Fiscal Year
2006
Total Cost
$213,665
Indirect Cost

  Institution

Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
078200995
City
Seattle
State
WA
Country
United States
Zip Code
98109

  Publications

Nielsen, Christopher E; Wang, Xihai; Robinson, Robert J et al. (2014) Carcinogenic and inflammatory effects of plutonium-nitrate retention in an exposed nuclear worker and beagle dogs. Int J Radiat Biol 90:60-70
Venkataraman, G M; Geraghty, D; Fox, J et al. (2013) Canine DLA-79 gene: an improved typing method, identification of new alleles and its role in graft rejection and graft-versus-host disease. Tissue Antigens 81:204-11
Leko, Vid; Varnum-Finney, Barbara; Li, Hongzhe et al. (2012) SIRT1 is dispensable for function of hematopoietic stem cells in adult mice. Blood 119:1856-60
Nielsen, Christopher E; Wilson, Dulaney A; Brooks, Antone L et al. (2012) Microdistribution and long-term retention of 239Pu (NO3)4 in the respiratory tracts of an acutely exposed plutonium worker and experimental beagle dogs. Cancer Res 72:5529-36
Mielcarek, Marco; Storb, Rainer; Georges, George E et al. (2011) Mesenchymal stromal cells fail to prevent acute graft-versus-host disease and graft rejection after dog leukocyte antigen-haploidentical bone marrow transplantation. Biol Blood Marrow Transplant 17:214-25
Graves, Scott S; Stone, Diane M; Loretz, Carol et al. (2011) Antagonistic and agonistic anti-canine CD28 monoclonal antibodies: tools for allogeneic transplantation. Transplantation 91:833-40
Wilson, Dulaney A; Brigantic, Andrea; Morgan, William F (2011) The association of inbreeding with lung fibrosis incidence in Beagle dogs that inhaled 238PuO2 or 239PuO2. Radiat Res 176:781-6
Lee, Won Sik; Suzuki, Yasuhiro; Graves, Scott S et al. (2011) Canine bone marrow-derived mesenchymal stromal cells suppress alloreactive lymphocyte proliferation in vitro but fail to enhance engraftment in canine bone marrow transplantation. Biol Blood Marrow Transplant 17:465-75
Wang, Yong; Scheiber, Melissa N; Neumann, Carola et al. (2011) MicroRNA regulation of ionizing radiation-induced premature senescence. Int J Radiat Oncol Biol Phys 81:839-48
Pogosova-Agadjanyan, Era L; Fan, Wenhong; Georges, George E et al. (2011) Identification of radiation-induced expression changes in nonimmortalized human T cells. Radiat Res 175:172-84

Showing the most recent 10 out of 26 publications