The Administrative Core will provide support for research of high-throughput biodosimetry approaches which will be needed following a large-scale radiological event resulting in mass casualties from multiple types of radiation exposures. The purpose of the Administrative Core is to create and implement administrative and leadership mechanisms that will foster effective interactions among the CMCR investigators and institutions to ensure a productive research effort. It is also responsible for overall organization, management, decision making, periodic evaluations, data sharing and involvement of institutional resources. The objectives of the Administrative Core are to: ? Form an Administrative Structure to administer the CMCR: o Establish and coordinate an Internal Advisory Committee and an External Scientific Advisory Group o Facilitate collaboration between the various Scientific Projects and Cores within the Columbia CMCR o Facilitate collaboration between this CMCR and other CMCRs o Organize an annual retreat. ? Administer the budget; coordinate travel and purchasing. ? Coordinate patent applications and maintain intellectual property protections. ? Generate the CMCR Annual Report. ? Maintain the CMCR website.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
2U19AI067773-16
Application #
9940223
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2020-08-01
Budget End
2021-07-31
Support Year
16
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Type
DUNS #
621889815
City
New York
State
NY
Country
United States
Zip Code
10032
Laiakis, Evagelia C; Mak, Tytus D; Strawn, Steven J et al. (2018) Global metabolomic responses in urine from atm deficient mice in response to LD50/30 gamma irradiation doses. Environ Mol Mutagen 59:576-585
Eppensteiner, John; Davis, Robert Patrick; Barbas, Andrew S et al. (2018) Immunothrombotic Activity of Damage-Associated Molecular Patterns and Extracellular Vesicles in Secondary Organ Failure Induced by Trauma and Sterile Insults. Front Immunol 9:190
Vera, Nicholas B; Chen, Zhidan; Pannkuk, Evan et al. (2018) Differential mobility spectrometry (DMS) reveals the elevation of urinary acetylcarnitine in non-human primates (NHPs) exposed to radiation. J Mass Spectrom 53:548-559
Lacombe, Jerome; Sima, Chao; Amundson, Sally A et al. (2018) Candidate gene biodosimetry markers of exposure to external ionizing radiation in human blood: A systematic review. PLoS One 13:e0198851
Lee, Younghyun; Pujol Canadell, Monica; Shuryak, Igor et al. (2018) Candidate protein markers for radiation biodosimetry in the hematopoietically humanized mouse model. Sci Rep 8:13557
Rudqvist, Nils; Laiakis, Evagelia C; Ghandhi, Shanaz A et al. (2018) Global Gene Expression Response in Mouse Models of DNA Repair Deficiency after Gamma Irradiation. Radiat Res 189:337-344
Suresh Kumar, M A; Laiakis, Evagelia C; Ghandhi, Shanaz A et al. (2018) Gene Expression in Parp1 Deficient Mice Exposed to a Median Lethal Dose of Gamma Rays. Radiat Res 190:53-62
Zheng, Zhihong; Fan, Shengjun; Zheng, Jing et al. (2018) Inhibition of thioredoxin activates mitophagy and overcomes adaptive bortezomib resistance in multiple myeloma. J Hematol Oncol 11:29
Beach, Tyler A; Groves, Angela M; Johnston, Carl J et al. (2018) Recurrent DNA damage is associated with persistent injury in progressive radiation-induced pulmonary fibrosis. Int J Radiat Biol 94:1104-1115
Ghandhi, Shanaz A; Turner, Helen C; Shuryak, Igor et al. (2018) Whole thorax irradiation of non-human primates induces persistent nuclear damage and gene expression changes in peripheral blood cells. PLoS One 13:e0191402

Showing the most recent 10 out of 185 publications