The Training and Education Program Core has as its mission the training of talented postdoctoral fellows for careers in radiation biology research, specifically areas of development of new radiation protector and radiation mitigating agents. The Training and Education Program has as its goals the following aims: 1. Training postdoctoral fellows (as well as selected predoctoral candidates including technicians) in the use of assays, methods, reagents, animal models, and technology to study radiobiology and develop new products for entry into clinical use through the regulatory process. 2. Train researchers in the principles of radiobiology/epidemiology and safety through existing courses in radiobiology, radiation therapy physics, radiation counter-terrorism, and new seminar series to develop a base of knowledge in radiation biology. 3. Bring to the CMCR for educational expansion, speakers from other institutions and host seminars to faculty and students within the CMCR, and bring expertise and breadth of knowledge into the fields of development of new radiation protector and radiation mitigator drugs. 4. Mentor postdoctoral fellows (or appropriate graduate students) carefully in the basic principles of radiation biology with a goal toward fusing their training in basic chemistry into radiation biology to provide new careers in drug discovery specifically focused on radiation protector and radiation mitigator drugs.
Lou, Wenjia; Ting, Hsiu-Chi; Reynolds, Christian A et al. (2018) Genetic re-engineering of polyunsaturated phospholipid profile of Saccharomyces cerevisiae identifies a novel role for Cld1 in mitigating the effects of cardiolipin peroxidation. Biochim Biophys Acta Mol Cell Biol Lipids 1863:1354-1368 |
Anthonymuthu, Tamil S; Kenny, Elizabeth M; Lamade, Andrew M et al. (2018) Oxidized phospholipid signaling in traumatic brain injury. Free Radic Biol Med 124:493-503 |
Hassannia, Behrouz; Wiernicki, Bartosz; Ingold, Irina et al. (2018) Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma. J Clin Invest 128:3341-3355 |
Conrad, Marcus; Kagan, Valerian E; Bayir, Hülya et al. (2018) Regulation of lipid peroxidation and ferroptosis in diverse species. Genes Dev 32:602-619 |
Stoyanovsky, Anastas D; Stoyanovsky, Detcho A (2018) 1-Oxo-2,2,6,6-tetramethylpiperidinium bromide converts ?-H N,N-dialkylhydroxylamines to nitrones via a two-electron oxidation mechanism. Sci Rep 8:15323 |
Zhou, Shuanhu; Glowacki, Julie (2018) Dehydroepiandrosterone and Bone. Vitam Horm 108:251-271 |
Robinson, Andria R; Yousefzadeh, Matthew J; Rozgaja, Tania A et al. (2018) Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging. Redox Biol 17:259-273 |
Gaschler, Michael M; Andia, Alexander A; Liu, Hengrui et al. (2018) FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation. Nat Chem Biol 14:507-515 |
Tyurina, Yulia Y; Shrivastava, Indira; Tyurin, Vladimir A et al. (2018) ""Only a Life Lived for Others Is Worth Living"": Redox Signaling by Oxygenated Phospholipids in Cell Fate Decisions. Antioxid Redox Signal 29:1333-1358 |
Schlattner, Uwe; Tokarska-Schlattner, Malgorzata; Epand, Richard M et al. (2018) NME4/nucleoside diphosphate kinase D in cardiolipin signaling and mitophagy. Lab Invest 98:228-232 |
Showing the most recent 10 out of 203 publications