Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
1U19AI070345-01
Application #
7150230
Study Section
Special Emphasis Panel (ZAI1-SV-I (M1))
Project Start
2006-07-01
Project End
2011-07-31
Budget Start
2006-07-01
Budget End
2007-07-31
Support Year
1
Fiscal Year
2006
Total Cost
$93,838
Indirect Cost
Name
Johns Hopkins University
Department
Type
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
MacGlashan Jr, Donald (2016) Stability of Syk protein and mRNA in human peripheral blood basophils. J Leukoc Biol 100:535-43
Sterba, Patricia M; Hamilton, Robert G; Saini, Sarbjit S (2015) Suppression of basophil Fc?RI activation by serum from active chronic idiopathic/spontaneous urticaria (CIU/CSU) subjects. J Invest Dermatol 135:1454-1456
Narisety, Satya D; Frischmeyer-Guerrerio, Pamela A; Keet, Corinne A et al. (2015) A randomized, double-blind, placebo-controlled pilot study of sublingual versus oral immunotherapy for the treatment of peanut allergy. J Allergy Clin Immunol 135:1275-82.e1-6
Gorelik, Mark; Narisety, Satya D; Guerrerio, Anthony L et al. (2015) Suppression of the immunologic response to peanut during immunotherapy is often transient. J Allergy Clin Immunol 135:1283-92
McGowan, Emily C; Savage, Jessica H; Courneya, Jean-Paul et al. (2014) Relationship of IgE to basophil phenotypes in peanut-sensitized adults. J Allergy Clin Immunol 134:746-749.e6
Macglashan Jr, Donald W; Saini, Sarbjit S (2013) Omalizumab increases the intrinsic sensitivity of human basophils to IgE-mediated stimulation. J Allergy Clin Immunol 132:906-11.e1-4
Saini, Sarbjit S; MacGlashan Jr, Donald W (2012) Assessing basophil functional measures during monoclonal anti-IgE therapy. J Immunol Methods 383:60-4
MacGlashan Jr, D (2012) Subthreshold desensitization of human basophils re-capitulates the loss of Syk and Fc?RI expression characterized by other methods of desensitization. Clin Exp Allergy 42:1060-70
MacGlashan Jr, Donald W (2012) IgE-dependent signaling as a therapeutic target for allergies. Trends Pharmacol Sci 33:502-9
Savage, Jessica H; Courneya, Jean-Paul; Sterba, Patricia M et al. (2012) Kinetics of mast cell, basophil, and oral food challenge responses in omalizumab-treated adults with peanut allergy. J Allergy Clin Immunol 130:1123-1129.e2

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