Administrative Core The Administrative Core will provide the scientific leadership and organizational management to assure that the program project: """"""""Basic and Comparative Studies of CCR5 Inhibition to Prevent HIV Transmission"""""""" meets its objectives effectively by: * Developing an organizational structure that assures effective scientific leadership. * The fiscal and administrative management of the program, including grant reporting requirements, accounting and sub-contracts that includes coordination of communications with NIH and with industry collaborators and assuring seamless coordination of access to resources within the program to assure their timely and cost-efficient utilization to assist in project completion. * Coordination of communication among all project investigators and institutional administrations located at multiple institutions and the scientific advisory panel. This will include organizing team meetings, conference calls and recording and distributing minutes of calls and distribution of presentations. * Maintaining a system to promote sharing of research output of the group that includes maintaining a web site for Project documents, methods, manuscripts, publications, slide presentations and other key information on program progress. * Monitoring scientific productivity, assuring appropriate resource allocation and establishing a mechanism for resolution of any conflicts should they arise. * Provide statistical support for the projects within the IPCP application at the conceptual, development, conduction and analysis stages

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI076981-03
Application #
8066956
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2010-06-01
Budget End
2011-05-31
Support Year
3
Fiscal Year
2010
Total Cost
$166,468
Indirect Cost
Name
Case Western Reserve University
Department
Type
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Veazey, Ronald S; Ling, Binhua (2017) Short Communication: Comparative Susceptibility of Rhesus Macaques of Indian and Chinese Origin to Vaginal Simian-Human Immunodeficiency Virus Transmission as Models for HIV Prevention Research. AIDS Res Hum Retroviruses 33:1199-1201
Veazey, R S; Pilch-Cooper, H A; Hope, T J et al. (2016) Prevention of SHIV transmission by topical IFN-? treatment. Mucosal Immunol 9:1528-1536
Xu, Huanbin; Wang, Xiaolei; Malam, Naomi et al. (2016) Persistent Simian Immunodeficiency Virus Infection Drives Differentiation, Aberrant Accumulation, and Latent Infection of Germinal Center Follicular T Helper Cells. J Virol 90:1578-87
Xu, Huanbin; Wang, Xiaolei; Malam, Naomi et al. (2015) Persistent Simian Immunodeficiency Virus Infection Causes Ultimate Depletion of Follicular Th Cells in AIDS. J Immunol 195:4351-7
Hadzic, Sarah V; Wang, Xiaolei; Dufour, Jason et al. (2014) Comparison of the vaginal environment of Macaca mulatta and Macaca nemestrina throughout the menstrual cycle. Am J Reprod Immunol 71:322-9
Wang, Nick X; Sieg, Scott F; Lederman, Michael M et al. (2013) Using glycosaminoglycan/chemokine interactions for the long-term delivery of 5P12-RANTES in HIV prevention. Mol Pharm 10:3564-73
Ahsan, Muhammad H; Gill, Amy F; Alvarez, Xavier et al. (2013) Kinetics of liver macrophages (Kupffer cells) in SIV-infected macaques. Virology 446:77-85
Xu, Huanbin; Wang, Xiaolei; Lackner, Andrew A et al. (2013) CD8 down-regulation and functional impairment of SIV-specific cytotoxic T lymphocytes in lymphoid and mucosal tissues during SIV infection. J Leukoc Biol 93:943-50
Veazey, Ronald S (2013) Animal models for microbicide safety and efficacy testing. Curr Opin HIV AIDS 8:295-303
Dinh, Minh H; Okocha, Eneniziaogochukwu A; Koons, Ann et al. (2012) Expression of structural proteins in human female and male genital epithelia and implications for sexually transmitted infections. Biol Reprod 86:32

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