The Administrative Core will serve all Projects and Cores of AADCRC U19 Center Program and will bedirected by Dr. David Peden, P.I. for this U19 program. Biostatistical support and advice on datamanagement will be provided through this core by Dr. Haibo Zhou, Director of the Biostatistics Core forthe UNC Center for Environmental Medicine, Asthma & Lung Biology (of which Dr. Peden is the Director).Data management support will be provided by this core which is funded by NIH and EPA funds. TheAdministrative Core will be responsible for the day-to-day administration and program coordination andongoing evaluation of the U19. The functions of the Administrative Core will include all administrative andfinancial aspects which will include the timely disbursal of funds, submission of reports, assembling andkeeping track of program materials and reports, and scheduling meetings of all leaders of Cores andProjects of the U19. Dr. Peden, as Principal Investigator will participate in Steering Committee meetingsand other AADCRC activities. The Administrative Core budget includes travel funds for the PrincipalInvestigator to participate in annual Steering Committee meetings, and for the PI and Core and Projectleaders to attend an annual two-day AADCRC scientific meeting to be held in conjunction with theSteering Committee meeting in Bethesda, Maryland. Coordination of clinical relevance of the projects willbe overseen by Dr. Peden who will review and assist in development of all clinical research protocols withthe IRB, GCRC and EPA. Data from animal studies will inform development of these protocols. Weeklyprotocol review meetings and lab meetings will be conducted by Dr. Peden and Dr. Ting, who will serveas the Co-Pi of the U19. Dr. Peden will also coordinate access to existing NIH funded SampleAcquisition, Analysis, and Repository Core Facility of the Center for Environmental Medicine, Asthma &Lung Biology (headed by Dr. Alexis). These existing cores will provide support for sample analysis ofnucleotides in airway fluids and for soluble protein profiling by flow cytometry of airway and blood cells.
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| Kang, Min-Jong; Yoon, Chang Min; Kim, Bo Hye et al. (2015) Suppression of NLRX1 in chronic obstructive pulmonary disease. J Clin Invest 125:2458-62 |
| Aleman, Maria M; Mills, Katherine; Almond, Martha et al. (2015) Reply: To PMID 25195169. J Allergy Clin Immunol 135:836-7 |
| Wu, Weidong; Wages, Phillip A; Devlin, Robert B et al. (2015) SRC-mediated EGF receptor activation regulates ozone-induced interleukin 8 expression in human bronchial epithelial cells. Environ Health Perspect 123:231-6 |
| Hernandez, Michelle L; Mills, Katherine; Almond, Martha et al. (2015) IL-1 receptor antagonist reduces endotoxin-induced airway inflammation in healthy volunteers. J Allergy Clin Immunol 135:379-85 |
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