This ICEMR program endeavors to achieve a better understanding of malaria epidemiology, vector biology, and mechanisms of artemisinin resistance in Southeast Asia so that more effective, targeted malaria control can be achieved through a combination of accurate surveillance of the disease, integrated vector control, and more effective chemotherapy in this region. The involvement of a large number of key investigators from multiple institutions from the U.S., Thailand, and China, and our strategic selection of mulfiple study sites in China, Myanmar and Thailand require effective administration of the program. To meet this challenge, this administrative core is established to 1) provide administrative support for managing, coordinating, and supervising the research activities of this program;2) provide financial oversight of grant accounting at participating domestic and foreign institutions;and 3) provide effective administrative management of training components ofthis program. We have developed an administrative structure and procedures for managing and coordinating all research and training activities. This administrative core will facilitate research-related activities of the program, assist in the organization of ICEMR-related meetings, and develop and submit annual progress and flnancial reports. In addition to the significant dedication of the program director and codirectors in the overall administration, we have also designated in-country coordinators to further enhance daily supervision and coordination of the scientific activities at the study sites. While this core will provide overall flnancial administration of the program, a centralized flnancial administration at the endemic countries will be used to provide additional flnancial oversight. For the training component of this program, this core will provide administrative support for the career development projects and all other training activities within this program. The extensive collaborations and existing research and training projects among the participating institutions provide us the experience and established mechanisms for the successful administrafion ofthis program.
This administrative core aims to provide effective administration and coordination of all scientiflc activities, financial oversight of grant accounting, and management of training activities of this program.
|Bunditvorapoom, Duangkamon; Kochakarn, Theerarat; Kotanan, Namfon et al. (2018) Fitness Loss under Amino Acid Starvation in Artemisinin-Resistant Plasmodium falciparum Isolates from Cambodia. Sci Rep 8:12622|
|Siddiqui, Faiza A; Cabrera, Mynthia; Wang, Meilian et al. (2018) Plasmodium falciparum Falcipain-2a Polymorphisms in Southeast Asia and Their Association With Artemisinin Resistance. J Infect Dis 218:434-442|
|Yang, Henglin; Wang, Jingyan; Liu, Hui et al. (2018) Randomized, Double-Blind, Placebo-Controlled Studies to Assess Safety and Prophylactic Efficacy of Naphthoquine-Azithromycin Combination for Malaria Prophylaxis in Southeast Asia. Antimicrob Agents Chemother 62:|
|Chaverra-Rodriguez, Duverney; Macias, Vanessa M; Hughes, Grant L et al. (2018) Targeted delivery of CRISPR-Cas9 ribonucleoprotein into arthropod ovaries for heritable germline gene editing. Nat Commun 9:3008|
|Mbenda, Huguette Gaelle Ngassa; Zeng, Weilin; Bai, Yao et al. (2018) Genetic diversity of the Plasmodium vivax phosphatidylinositol 3-kinase gene in two regions of the China-Myanmar border. Infect Genet Evol 61:45-52|
|Bai, Yao; Zhang, Jiaqi; Geng, Jinting et al. (2018) Longitudinal surveillance of drug resistance in Plasmodium falciparum isolates from the China-Myanmar border reveals persistent circulation of multidrug resistant parasites. Int J Parasitol Drugs Drug Resist 8:320-328|
|Zhao, Yan; Zeng, Jie; Zhao, Yonghong et al. (2018) Risk factors for asymptomatic malaria infections from seasonal cross-sectional surveys along the China-Myanmar border. Malar J 17:247|
|Deng, Zeshuai; Li, Qing; Yi, Haoan et al. (2018) Hemoglobin E protects against acute Plasmodium vivax infections in a Kachin population at the China-Myanmar border. J Infect 77:435-439|
|Zhong, Daibin; Koepfli, Cristian; Cui, Liwang et al. (2018) Molecular approaches to determine the multiplicity of Plasmodium infections. Malar J 17:172|
|Sriwichai, Patchara; Karl, Stephan; Samung, Yudthana et al. (2017) Imported Plasmodium falciparum and locally transmitted Plasmodium vivax: cross-border malaria transmission scenario in northwestern Thailand. Malar J 16:258|
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