The Shared Technology Cores in the USA and India will provide services to multiple projects of this ICEMR grant. These services include sequencing, genotyping of multiple organisms (including humans, parasites, and mosquitoes), microarray infrastructure and analysis, and microfluidic fabrication at The Center Genomic Applications (TCGA) and the University of Washington (UW).

Public Health Relevance

TO OVERALL APPLICATION: Due to the reliance of all projects on the isolation and characterization of parasites exhibiting the Accelerated Resistance to Multiple Drugs (ARMD) phenotype, genotyping facilities will be of central importance. In addition, central aims of Project 3 depend on the fabrication of microfluidic devices to assess erythrocyte deformability following Plasmodium Invasion. Lastly, mosquito transcriptomics in Project 4 and genome-wide association studies in Project 5 will require extensive microarray infrastructure provided by this core.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
1U19AI089688-01
Application #
8005349
Study Section
Special Emphasis Panel (ZAI1-AWA-M (M1))
Project Start
2010-07-01
Project End
2017-06-30
Budget Start
2010-07-01
Budget End
2011-06-30
Support Year
1
Fiscal Year
2010
Total Cost
$235,190
Indirect Cost
Name
University of Washington
Department
Type
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
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