The Administrative Core, led by Dr. Pascal Poignard, will provide general management and administrative support for all Projects and Cores under the U-19 Grant. Additionally, this Core will coordinate an Administrative Partnership Plan to maintain timely and good communications across various external researchers, advisors and stakeholders related to HIV B cell immunology. These goals will be met by completing the following Specific Aims: General Management and Administration 1. Maintain good Project and Core integration via coordinated project management to track progress, troubleshoot problems and facilitate achievement of grant goals;regular intra-grant communication via annual meetings, teleconferences/web conferences, and establishment of a web-enabled project portal;and the timely review of data and progress with key scientific and grant partners. 2. Ensure that lAVI administrative resources are accessed and in place for financial management, grants management, business development and intellectual property management. Administrative Partnership Plan 3. Establish an External Scientific Advisory Panel (ESAP) which will conduct an annual review of progress, provide scientific input and ensure timely and proper reporting to NIH/NIH Program Officials. 4. Host and actively participate in annual B cell Immunology Partnership Program for HIV-1 Vaccine Discovery Workshops to ensure dissemination and collaboration with other U-19 grantees, other NIH grantees and HIV researchers in the area of B cell immunology.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
1U19AI090970-01
Application #
8042881
Study Section
Special Emphasis Panel (ZAI1-PTM-A (M4))
Project Start
2010-09-01
Project End
2015-08-31
Budget Start
2010-09-01
Budget End
2011-08-31
Support Year
1
Fiscal Year
2010
Total Cost
$75,839
Indirect Cost
Name
International AIDS Vaccine Initiative
Department
Type
DUNS #
020790895
City
New York
State
NY
Country
United States
Zip Code
Wagner, Gabriel A; Landais, Elise; Caballero, Gemma et al. (2017) Intrasubtype B HIV-1 Superinfection Correlates with Delayed Neutralizing Antibody Response. J Virol 91:
Landais, Elise; Murrell, Ben; Briney, Bryan et al. (2017) HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage. Immunity 47:990-1003.e9
Landais, Elise; Huang, Xiayu; Havenar-Daughton, Colin et al. (2016) Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort. PLoS Pathog 12:e1005369
Var, Susanna R; Day, Tyler R C; Vitomirov, Andrej et al. (2016) Mitochondrial injury and cognitive function in HIV infection and methamphetamine use. AIDS 30:839-48
Karris, Maile Y; Umlauf, Anya; Vaida, Florin et al. (2016) A randomized controlled clinical trial on the impact of CCR5 blockade with maraviroc in early infection on T-cell dynamics. Medicine (Baltimore) 95:e5315
MacLeod, Daniel T; Choi, Nancy M; Briney, Bryan et al. (2016) Early Antibody Lineage Diversification and Independent Limb Maturation Lead to Broad HIV-1 Neutralization Targeting the Env High-Mannose Patch. Immunity 44:1215-26
Krumm, Stefanie A; Mohammed, Hajer; Le, Khoa M et al. (2016) Mechanisms of escape from the PGT128 family of anti-HIV broadly neutralizing antibodies. Retrovirology 13:8
Murrell, Ben; Weaver, Steven; Smith, Martin D et al. (2015) Gene-wide identification of episodic selection. Mol Biol Evol 32:1365-71
Carter, Christoph C; Wagner, Gabriel A; Hightower, George K et al. (2015) HIV-1 neutralizing antibody response and viral genetic diversity characterized with next generation sequencing. Virology 474:34-40
Frost, Simon D W; Murrell, Ben; Hossain, A S Md Mukarram et al. (2015) Assigning and visualizing germline genes in antibody repertoires. Philos Trans R Soc Lond B Biol Sci 370:

Showing the most recent 10 out of 42 publications