The Pilot Research Project Program for the University of Rochester's Center for Medical Countermeasures against Radiation (CMCR) is designed to identify and fund innovafive pilot studies in radiation-related research, with an emphasis on the basic science supporting drug development to counter injuries that would result from a radiological dispersal device (RDD) or a nuclear detonafion. These pilot projects are solicited from Institufions both within and outside of the CMCR Network through several approaches, including direct email solicitafion and online announcement by the Radiafion Research Society (RRS) to its full membership, as well as announcement on both the UR CMCR website and the nafional NIH/NIAID/CMCR website. As an indicafion of the breadth of our announcement efforts and the diversity of applicafions we attract, over the course of the previous funding period the UR CMCR received a total of 74 applicafions from 32 institutions worldwide (includino from Canada. China, France. Israel, and Japan).

Public Health Relevance

As we confinue on with our Pilot program, we will build upon Its real scientific success: our current Center applicafion is the product of mature collaborafions with our Pilot awardees. Our new Center has as its anchor the confinuafion of the CBARMFI Lung Toxicity and Inhalafion research (Jacob Finkelstein and Jacqueline Williams?Project 1), while the remaining Projects were originally nurtured by our CBARMFI Pilot Research Program 2005-2010;indeed, Drs. Kerry O'Banion and John Olschowka (Project 2?Brain), Edith Lord and Julie Ryan (Project 3?Skin and Immunology), and James Palis (Project 4?Bone Marrow) were an CBARMFI Pilot award recipients. These invesfigators have been sharing tissues and data, discussing experimental design, and serving as mutual scientific advisors for several years as part of their work in CBARMFI: the true nature of collaborafion.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Research Program--Cooperative Agreements (U19)
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University of Rochester
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