Abstract

The overall goals of the administrative core, headed by Principal Investigator Dr. James Gern, are to provide leadership and the organizational backbone for the program project entitled ?Viral and Environmental Environmental Determinants of Rhinovirus Illness Severity ?. The objectives of the core include promoting interaction and collaboration between the Projects and Cores, maintaining close communication between investigators in Wisconsin sites (LaFarge, Madison, Marshfield) and San Francisco, coordinating its interaction with external entities (e.g. External Review Committee, Consultants, NIAID, other AADCRC cooperative research centers) and providing optimal management of fiscal and other program resources. By achieving these objectives, the Administrative Core will optimize use of scientific and fiscal resources and facilitate scientific interaction and discovery.

Public Health Relevance

The research program entitled ?Viral and Environmental Determinants of Rhinovirus Illness Severity? has an Administrative Core to help coordinate the activities of the two scientific projects and two service cores that comprise the program. The duties of the Administrative core include ensuring good communication between these program components, overseeing fiscal and scientific resources, and providing leadership to facilitate scientific advances related to the respiratory health of children.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19AI104317-09
Application #
10091390
Study Section
Special Emphasis Panel (ZAI1)
Project Start
2013-02-01
Project End
2023-01-31
Budget Start
2021-02-01
Budget End
2022-01-31
Support Year
9
Fiscal Year
2021
Total Cost
Indirect Cost

  Institution

Name
University of Wisconsin Madison
Department
Type
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715

  Publications

Yang, Zhonghui; Bochkov, Yury A; Voelker, Dennis R et al. (2018) Identification of a Novel Inhibitor of HRV Replication and Inflammation in Airway Epithelial Cells. Am J Respir Cell Mol Biol :
Hasegawa, Kohei; Jartti, Tuomas; Bochkov, Yury A et al. (2018) Rhinovirus Species in Children with Severe Bronchiolitis: Multicenter Cohort Studies in the US and Finland. Pediatr Infect Dis J :
Yin, John; Redovich, Jacob (2018) Kinetic Modeling of Virus Growth in Cells. Microbiol Mol Biol Rev 82:
Scully, Erik J; Basnet, Sarmi; Wrangham, Richard W et al. (2018) Lethal Respiratory Disease Associated with Human Rhinovirus C in Wild Chimpanzees, Uganda, 2013. Emerg Infect Dis 24:267-274
Ludka-Gaulke, Tiffany; Ghera, Princy; Waring, Stephen C et al. (2018) Farm exposure in early childhood is associated with a lower risk of severe respiratory illnesses. J Allergy Clin Immunol 141:454-456.e4
Teo, Shu Mei; Tang, Howard H F; Mok, Danny et al. (2018) Airway Microbiota Dynamics Uncover a Critical Window for Interplay of Pathogenic Bacteria and Allergy in Childhood Respiratory Disease. Cell Host Microbe 24:341-352.e5
Bashir, Hiba; Grindle, Kristine; Vrtis, Rose et al. (2018) Association of rhinovirus species with common cold and asthma symptoms and bacterial pathogens. J Allergy Clin Immunol 141:822-824.e9
Kim, Chang Keun; Callaway, Zak; Gern, James E (2018) Viral Infections and Associated Factors That Promote Acute Exacerbations of Asthma. Allergy Asthma Immunol Res 10:12-17
Gern, James E; Lee, Wai Ming; Swenson, Cheri A et al. (2018) Development of a Rhinovirus Inoculum using a Reverse Genetics Approach. J Infect Dis :
Leino, Annamari; Lukkarinen, Minna; Turunen, Riitta et al. (2018) Pulmonary function and bronchial reactivity 4 years after the first virus-induced wheezing. Allergy :

Showing the most recent 10 out of 61 publications