Purpose: The Bastyr University/University of Washington PCCTR Oncomycology Research Center will investigate the immunologic and antitumor effects of Trametes versicolor (Tv) a traditional Chinese medicine medicinal mushroom, for use in the treatment of cancer patients in the US. The past 6 years of research at our NCCAM-funded Developmental Center for Research in CAM (DCRC) led us to conclude that the immunomodulating mushroom Tv, widely used by Japanese oncologists, may be an effective adjunctive immune therapy because of its targeted activation of the innate and adaptive immune system via TOll-lil

Public Health Relevance

The Asian medicinal mushroom, Trametes versicolor (PSK), is a potentially important immune therapy for breast and prostate cancer. The DCRC center (2005-2009) elucidated the TLR mechanism of action of PSK. In the next 4 years of the PCCTR center we will be the first to conduct clinical trials of PSK in US cancer patients.

National Institute of Health (NIH)
National Center for Complementary & Alternative Medicine (NCCAM)
Research Program--Cooperative Agreements (U19)
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Special Emphasis Panel (ZAT1-SM (20))
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Pontzer, Carol H
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Bastyr University
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