The administrative Core A is responsible for providing all of the administrative support for the PPG. These responsibilities, carried out by the Administrative Coordinator (Ms. Eleni Yokas) under the supervision of the PI (M. F. Goodman), will consist of recruitment of staff and students for the individual projects and other two cores, arrange a calender of PPG internal and external seminars, arrange transportation, lodging and meeting facilities for the project leaders, key investigators, and consortium collaborators for the yearly PPG retreats at NIEHS and USC. A major task will be to handle the logistics for these retreats, that will bring together all of the PPG personnel with the three Scientific Advisory Panel members. Core A will interface with the Molecular and Computational Biology Section and the Chemistry Department at USC to schedule outside speakers, three per semester, as part of the two separate and well-established ongoing seminar series. Core A will also be responsible for scheduling special seminars. Core A will operate primarily at USC. However, since """"""""formal1 meetings will be held at NIEHS, and we further anticipate that several informal meetings will also take place at NIEHS, to take full advantage of their sophisticated 3D structural illustration laboratory facility, Sam Wilson will provide logistical support for these meetings, reserving conference rooms at NIEHS and lodging in Research Triangle Park.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program--Cooperative Agreements (U19)
Project #
5U19CA105010-09
Application #
8381146
Study Section
Special Emphasis Panel (ZCA1-GRB-S)
Project Start
Project End
Budget Start
2012-08-01
Budget End
2013-07-31
Support Year
9
Fiscal Year
2012
Total Cost
$38,388
Indirect Cost
$10,723
Name
University of Southern California
Department
Type
DUNS #
072933393
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Mondal, Dibyendu; Warshel, Arieh (2018) EF-Tu and EF-G are activated by allosteric effects. Proc Natl Acad Sci U S A 115:3386-3391
Shock, David D; Freudenthal, Bret D; Beard, William A et al. (2017) Modulating the DNA polymerase ? reaction equilibrium to dissect the reverse reaction. Nat Chem Biol 13:1074-1080
Yoon, Hanwool; Warshel, Arieh (2017) Simulating the fidelity and the three Mg mechanism of pol ? and clarifying the validity of transition state theory in enzyme catalysis. Proteins 85:1446-1453
Perera, Lalith; Beard, William A; Pedersen, Lee G et al. (2017) Hiding in Plain Sight: The Bimetallic Magnesium Covalent Bond in Enzyme Active Sites. Inorg Chem 56:313-320
Yoon, Hanwool; Kolev, Vesselin; Warshel, Arieh (2017) Validating the Water Flooding Approach by Comparing It to Grand Canonical Monte Carlo Simulations. J Phys Chem B 121:9358-9365
Perera, Lalith; Freudenthal, Bret D; Beard, William A et al. (2017) Revealing the role of the product metal in DNA polymerase ? catalysis. Nucleic Acids Res 45:2736-2745
Astumian, R Dean; Mukherjee, Shayantani; Warshel, Arieh (2016) The Physics and Physical Chemistry of Molecular Machines. Chemphyschem 17:1719-41
Matute, Ricardo A; Yoon, Hanwool; Warshel, Arieh (2016) Exploring the mechanism of DNA polymerases by analyzing the effect of mutations of active site acidic groups in Polymerase ?. Proteins 84:1644-1657
Yoon, Hanwool; Warshel, Arieh (2016) The control of the discrimination between dNTP and rNTP in DNA and RNA polymerase. Proteins 84:1616-1624
Vorobyov, Igor; Kim, Ilsoo; Chu, Zhen T et al. (2016) Refining the treatment of membrane proteins by coarse-grained models. Proteins 84:92-117

Showing the most recent 10 out of 95 publications