Abstract

In this project, the tools of clinical cognitive neuroscience and functional brain imaging will be used to systematically address fundamental questions about cognitive, neurobiological, neurodevelopmental and genetic aspects of autism. High functioning autistic individuals (matched with healthy subjects) will participate in laboratory studies of sensorimotor aspects of eye movement control, executive cognitive skills subserved by prefrontal systems, and psychophysical studies of auditory and visual sensory abilities. Some of the subjects will also participate in fMRI studies that will individually address separate domains of the deficits.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Program--Cooperative Agreements (U19)
Project #
2U19HD035469-06
Application #
6684196
Study Section
Special Emphasis Panel (ZHD1)
Project Start
2002-09-26
Project End
2007-05-31
Budget Start
Budget End
Support Year
6
Fiscal Year
2002
Total Cost
Indirect Cost

  Institution

Name
University of Pittsburgh
Department
Type
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213

  Publications

Lynn, Andrew C; Padmanabhan, Aarthi; Simmonds, Daniel et al. (2018) Functional connectivity differences in autism during face and car recognition: underconnectivity and atypical age-related changes. Dev Sci 21:
Heymann, Perrine; Northrup, Jessie B; West, Kelsey L et al. (2018) Coordination is key: Joint attention and vocalisation in infant siblings of children with Autism Spectrum Disorder. Int J Lang Commun Disord 53:1007-1020
Iverson, Jana M; Northrup, Jessie B; Leezenbaum, Nina B et al. (2018) Early Gesture and Vocabulary Development in Infant Siblings of Children with Autism Spectrum Disorder. J Autism Dev Disord 48:55-71
West, Kelsey L; Leezenbaum, Nina B; Northrup, Jessie B et al. (2017) The Relation Between Walking and Language in Infant Siblings of Children With Autism Spectrum Disorder. Child Dev :
LeBarton, Eve Sauer; Iverson, Jana M (2016) Associations between gross motor and communicative development in at-risk infants. Infant Behav Dev 44:59-67
Focaroli, Valentina; Taffoni, Fabrizio; Parsons, Shelby M et al. (2016) Performance of Motor Sequences in Children at Heightened vs. Low Risk for ASD: A Longitudinal Study from 18 to 36 Months of Age. Front Psychol 7:724
O'Hearn, Kirsten; Velanova, Katerina; Lynn, Andrew et al. (2016) Abnormalities in brain systems supporting individuation and enumeration in autism. Autism Res 9:82-96
LeBarton, Eve Sauer; Iverson, Jana M (2016) Gesture development in toddlers with an older sibling with autism. Int J Lang Commun Disord 51:18-30
Mosconi, Matthew W; Sweeney, John A (2015) Sensorimotor dysfunctions as primary features of autism spectrum disorders. Sci China Life Sci 58:1016-23
Northrup, Jessie B; Iverson, Jana M (2015) Vocal Coordination During Early Parent-Infant Interactions Predicts Language Outcome in Infant Siblings of Children with Autism Spectrum Disorder. Infancy 20:523-547

Showing the most recent 10 out of 59 publications