Abstract

The Analytical Resources Core is composed of four subcores: 1) Hormone Assay; 2) Lipids, Lipoproteins, and Atherosclerosis; 3) Pathology; and 4) Amino Acid and Carbohydrate. These subcores will share resources with established VUSM cores, where they have served to streamline research activities, produce cost-effective lines of experimentation, foster collaborative enterprises, and provide alternative outlets to scientists research the technical limits in their own laboratories. The services offered by each subcore will be unique in their application to the mouse where great effort has been made to establish assay specificity and scale down sample size to accommodate samples from species. Each subcore has a longstanding expertise in diabetes and related disorders, with the exception of the Pathology Subcore. The start of the MMPC will provide the valuable and much needed opportunity of applying novel pathology resources to issues related to diabetes and metabolism.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Resource-Related Research Projects--Cooperative Agreements (U24)
Project #
5U24DK059637-02
Application #
6602418
Study Section
Special Emphasis Panel (ZDK1)
Project Start
2002-07-01
Project End
2003-06-30
Budget Start
Budget End
Support Year
2
Fiscal Year
2002
Total Cost
Indirect Cost

  Institution

Name
Vanderbilt University Medical Center
Department
Type
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37203

  Publications

Herrick, Mary K; Favela, Kristin M; Simerly, Richard B et al. (2018) Attenuation of diet-induced hypothalamic inflammation following bariatric surgery in female mice. Mol Med 24:56
Lewis Jr, James S; Shelton, Jeremy; Kuhs, Krystle Lang et al. (2018) p16 Immunohistochemistry in Oropharyngeal Squamous Cell Carcinoma Using the E6H4 Antibody Clone: A Technical Method Study for Optimal Dilution. Head Neck Pathol 12:440-447
Hunter, Roger W; Hughey, Curtis C; Lantier, Louise et al. (2018) Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase. Nat Med 24:1395-1406
Perez, Katia M; Curley, Kathleen L; Slaughter, James C et al. (2018) Glucose Homeostasis and Energy Balance in Children With Pseudohypoparathyroidism. J Clin Endocrinol Metab 103:4265-4274
Creecy, Amy; Uppuganti, Sasidhar; Unal, Mustafa et al. (2018) Low bone toughness in the TallyHO model of juvenile type 2 diabetes does not worsen with age. Bone 110:204-214
Babaev, Vladimir R; Ding, Lei; Zhang, Youmin et al. (2018) Loss of 2 Akt (Protein Kinase B) Isoforms in Hematopoietic Cells Diminished Monocyte and Macrophage Survival and Reduces Atherosclerosis in Ldl Receptor-Null Mice. Arterioscler Thromb Vasc Biol :ATVBAHA118312206
Zhang, Ming-Zhi; Wang, Suwan; Wang, Yinqiu et al. (2018) Renal Medullary Interstitial COX-2 (Cyclooxygenase-2) Is Essential in Preventing Salt-Sensitive Hypertension and Maintaining Renal Inner Medulla/Papilla Structural Integrity. Hypertension 72:1172-1179
Kjøbsted, Rasmus; Hingst, Janne R; Fentz, Joachim et al. (2018) AMPK in skeletal muscle function and metabolism. FASEB J 32:1741-1777
Santos Guasch, Gabriela L; Beeler, J Scott; Marshall, Clayton B et al. (2018) p73 Is Required for Ovarian Follicle Development and Regulates a Gene Network Involved in Cell-to-Cell Adhesion. iScience 8:236-249
Russart, Kathryn L G; Huk, Danielle; Nelson, Randy J et al. (2018) Elevated aggressive behavior in male mice with thyroid-specific Prkar1a and global Epac1 gene deletion. Horm Behav 98:121-129

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