. The Administrative Core, comprising the Director, the Program Coordinator and the administrative manager, will provide oversight for the program. They will prepare and administer all aspects of the budget and provide progress reports to the NIH. They will provide support to the other four cores of the Center, and oversee compliance with biosafety regulations, as well as the security of materials, data and facilities. Administrative support personnel will also perform day-to-day activities and operations of the Center such as organization of seminars, outreach activities and point of contact for questions from the scientific community and general public. Program Director Fiehn and Coordinator Wikoff will provide overall management of the West Coast Central Comprehensive Metabolomics Resource Core. They will implement monthly Steering Committee meetings as platform for core leaders to share developments and services, research progress and new applications. The Administrative Core will oversee the overall budget, technical services, outreach activities, and establish a reasonable cost-recovery fee schedule including campus approvals, and manage workflow records. The Administrative Core will coordinate data and information transfer to the Data Center (DRCC) and serve as a liaison to NIH, campus administration, other campus units, and other RCMRCs. They will monitor and regularly review the quality of services and prepare progress reports. The Center Director will assume overall responsibility for the timely conduct of research and outreach services and ensure annual milestones are met In order to maintain detailed information on all activities, the Administrative Core will implement a central LIMS system for all samples that are received in the Center for service activities or Pilot &Feasibility projects. The LIMS system will be used to summarize services and advancement projects taking place in each core. Importantly, the Core will also provide web services and metabolomic information. The Administrative Core will develop and maintain a website for the RCMRC that links to the NIH Common Fund website for the Metabolomics Program. The Center web site will be organized by a content management system to provide direct access for the Core leaders to upload content to the Core's services and projects. The web site will provide overviews on all services rendered by the Center as a one-stop site, including tutorials and videos.

Public Health Relevance

Good management is critical for success of centers and consortia. In order to provide cutting-edge services to the scientific community, including education of the general public through web-based tutorials on metabolism and metabolic diseases such as diabetes, this management team will enable the overall Center to provide tool developments, advancements and applications of comprehensive analysis of metabolism.

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Fong, Louise Y; Jing, Ruiyan; Smalley, Karl J et al. (2018) Human-like hyperplastic prostate with low ZIP1 induced solely by Zn deficiency in rats. Proc Natl Acad Sci U S A 115:E11091-E11100
Pedersen, Theresa L; Newman, John W (2018) Establishing and Performing Targeted Multi-residue Analysis for Lipid Mediators and Fatty Acids in Small Clinical Plasma Samples. Methods Mol Biol 1730:175-212
Ha, Yun-Sok; Kim, Yeon-Yong; Yu, Na Hee et al. (2018) Down-regulation of transient receptor potential melastatin member 7 prevents migration and invasion of renal cell carcinoma cells via inactivation of the Src and Akt pathway. Investig Clin Urol 59:263-274
Gao, Bei; Gallagher, Tara; Zhang, Ying et al. (2018) Tracking Polymicrobial Metabolism in Cystic Fibrosis Airways: Pseudomonas aeruginosa Metabolism and Physiology Are Influenced by Rothia mucilaginosa-Derived Metabolites. mSphere 3:
Killion, Elizabeth A; Reeves, Andrew R; El Azzouny, Mahmoud A et al. (2018) A role for long-chain acyl-CoA synthetase-4 (ACSL4) in diet-induced phospholipid remodeling and obesity-associated adipocyte dysfunction. Mol Metab 9:43-56
Garratt, Michael; Lagerborg, Kim A; Tsai, Yi-Miau et al. (2018) Male lifespan extension with 17-? estradiol is linked to a sex-specific metabolomic response modulated by gonadal hormones in mice. Aging Cell :e12786
Nagy-Szakal, Dorottya; Barupal, Dinesh K; Lee, Bohyun et al. (2018) Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics. Sci Rep 8:10056
Gifford, Isaac; Battenberg, Kai; Vaniya, Arpana et al. (2018) Distinctive Patterns of Flavonoid Biosynthesis in Roots and Nodules of Datisca glomerata and Medicago spp. Revealed by Metabolomic and Gene Expression Profiles. Front Plant Sci 9:1463
Harris, Todd R; Kodani, Sean; Rand, Amy A et al. (2018) Celecoxib Does Not Protect against Fibrosis and Inflammation in a Carbon Tetrachloride-Induced Model of Liver Injury. Mol Pharmacol 94:834-841
Shearer, Gregory C; Borkowski, Kamil; Puumala, Susan L et al. (2018) Abnormal lipoprotein oxylipins in metabolic syndrome and partial correction by omega-3 fatty acids. Prostaglandins Leukot Essent Fatty Acids 128:1-10

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