The complex nature of the subjective experience of pain and lack of effective treatments for chronic pain has led to the ongoing ?opioid epidemic? (CITE). Converging lines of evidence suggest that the ongoing chronic pain and opioid crisis will be addressed by discovering novel, multimodal therapeutic approaches employing a solid research network to promote and conduct high quality, efficient clinical trials. In this proposal, we outline a Hub-spoke complex (California Clinical and Translational Pain Research Consortium (CCTPRC)) consisting of four University of California academic medical centers. These centers have considerable experience in pain management clinical trials, phenotyping and biomarker validation. Our network will leverage solid existing CTSA resources to make clinical trial execution efficient and rapid. The Hub will be located at the University of California San Diego with spokes located on the other three campuses to provide maximum flexibility, ready to accommodate studies in a variety of pain conditions and provide successful recruitment and high-quality data collection.

Public Health Relevance

This proposal aims to outline the development of a Hub-spoke complex, The California Clinical and Translational Pain Research Consortium (CCTPRC) consisting of four University of California Universities. These centers have considerable experience in pain management clinical trials, phenotyping and biomarker validation, and integrative health initiatives. The Hub will be located at the University of California San Diego.

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Resource-Related Research Projects--Cooperative Agreements (U24)
Project #
1U24NS115714-01
Application #
9942319
Study Section
Special Emphasis Panel (ZNS1)
Program Officer
Karp, Barbara P
Project Start
2019-09-30
Project End
2024-03-31
Budget Start
2019-09-30
Budget End
2024-03-31
Support Year
1
Fiscal Year
2019
Total Cost
Indirect Cost
Name
University of California, San Diego
Department
Anesthesiology
Type
Schools of Medicine
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093