This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. DEVELOP PRODUCTION METHODS FOR CLINICAL GRADE LENTIVIRAL VECTOR.

Project Start
2005-09-01
Project End
2007-08-31
Budget Start
2005-09-01
Budget End
2007-08-31
Support Year
10
Fiscal Year
2006
Total Cost
$368,559
Indirect Cost
Name
Indiana University-Purdue University at Indianapolis
Department
Genetics
Type
Schools of Medicine
DUNS #
603007902
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Moullier, Philippe; Snyder, Richard O (2012) Recombinant adeno-associated viral vector reference standards. Methods Enzymol 507:297-311
Cornetta, Kenneth; Yao, Jing; Jasti, Aparna et al. (2011) Replication-competent lentivirus analysis of clinical grade vector products. Mol Ther 19:557-66
Lock, Martin; McGorray, Susan; Auricchio, Alberto et al. (2010) Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material. Hum Gene Ther 21:1273-85
Peters, B; Dirscherl, S; Dantzer, J et al. (2008) Automated analysis of viral integration sites in gene therapy research using the SeqMap web resource. Gene Ther 15:1294-8
Moullier, Philippe; Snyder, Richard O (2008) International efforts for recombinant adeno-associated viral vector reference standards. Mol Ther 16:1185-8
Cornetta, Kenneth; Reeves, Lilith; Cross, Scott (2008) Production of retroviral vectors for clinical use. Methods Mol Biol 433:17-32
Jin, Qingwen; Marsh, Jon; Cornetta, Kenneth et al. (2008) Resistance to human immunodeficiency virus type 1 (HIV-1) generated by lentivirus vector-mediated delivery of the CCR5{Delta}32 gene despite detectable expression of the HIV-1 co-receptors. J Gen Virol 89:2611-21
Zhang, Shangming; Joseph, Guiandre; Pollok, Karen et al. (2006) G2 cell cycle arrest and cyclophilin A in lentiviral gene transfer. Mol Ther 14:546-54
Cornetta, K; Matheson, L; Ballas, C (2005) Retroviral vector production in the National Gene Vector Laboratory at Indiana University. Gene Ther 12 Suppl 1:S28-35
Kahl, Christoph A; Pollok, Karen; Haneline, Laura S et al. (2005) Lentiviral vectors pseudotyped with glycoproteins from Ross River and vesicular stomatitis viruses: variable transduction related to cell type and culture conditions. Mol Ther 11:470-82

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