GLRCE Individual Career Development Support Program for Faculty awards (ICDSP-FA) are intended for mentored training and developmental research to firmly establish the career of junior faculty in biodefense and emerging infectious diseases research with focus on MAID Category A-C pathogens and their associated diseases. Goals of the ICDSP-FA program include the selection of promising investigators with faculty appointments at research institutions that are affiliated with the Center and their development as principal investigators of original, independent research programs for biodefense or emerging infectious diseases. ICDSP-FA projects are strongly encouraged to develop intrinsic translational values, for example the development of vaccines, the isolation of inhibitors for microbial drug targets and exploration of their therapeutic uses, or the research for new diagnostic principles of infectious diseases. The Center Director will assist faculty trainees in securing a GLRCE mentor who can guide the training and development of selected applicants. GLRCE periodically releases requests for proposals (RFPs) for ICDSP-FA projects by posting them on the GLRCE website and by sending RFP invitational e-mails to all Executive Board members, university research administration and departmental heads of research institutions affiliated with the Center. Particular emphasis is placed on seeking minorities and women faculty candidates for the selection of ICDSP-FA awards. Applications are reviewed and rank-ordered by the Executive Board, endorsed by the GLRCE Scientific Advisory Board, and approved by the NIAID RCE Program Management. Progress of the ICDSP-FA projects is closely monitored through monthly fiscal reporting, quarterly written progress reports, annual site visits, written annual reports/renewal applications as well as oral presentations at the Center's annual meeting. The Executive Board and Scientific Advisory Board together with the GLRCE Administrative Core's support will terminate funding for ICDSP-FA projects not demonstrating appropriate progress.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54AI057153-10
Application #
8448674
Study Section
Special Emphasis Panel (ZAI1-DDS-M)
Project Start
2013-03-01
Project End
2014-02-28
Budget Start
2013-03-01
Budget End
2014-02-28
Support Year
10
Fiscal Year
2013
Total Cost
$423,305
Indirect Cost
$117,560
Name
University of Chicago
Department
Type
DUNS #
005421136
City
Chicago
State
IL
Country
United States
Zip Code
60637
Hoang, Ky V; Rajaram, Murugesan V S; Curry, Heather Marie et al. (2018) Complement Receptor 3-Mediated Inhibition of Inflammasome Priming by Ras GTPase-Activating Protein During Francisella tularensis Phagocytosis by Human Mononuclear Phagocytes. Front Immunol 9:561
Mitchell, Anthony; Tam, Christina; Elli, Derek et al. (2017) Glutathionylation of Yersinia pestis LcrV and Its Effects on Plague Pathogenesis. MBio 8:
Chen, Grischa Y; McDougal, Courtney E; D'Antonio, Marc A et al. (2017) A Genetic Screen Reveals that Synthesis of 1,4-Dihydroxy-2-Naphthoate (DHNA), but Not Full-Length Menaquinone, Is Required for Listeria monocytogenes Cytosolic Survival. MBio 8:
Sloup, Rudolph E; Konal, Ashley E; Severin, Geoffrey B et al. (2017) Cyclic Di-GMP and VpsR Induce the Expression of Type II Secretion in Vibrio cholerae. J Bacteriol 199:
Kant, Sashi; Asthana, Shailendra; Missiakas, Dominique et al. (2017) A novel STK1-targeted small-molecule as an ""antibiotic resistance breaker"" against multidrug-resistant Staphylococcus aureus. Sci Rep 7:5067
Coulson, Garry B; Johnson, Benjamin K; Zheng, Huiqing et al. (2017) Targeting Mycobacterium tuberculosis Sensitivity to Thiol Stress at Acidic pH Kills the Bacterium and Potentiates Antibiotics. Cell Chem Biol 24:993-1004.e4
Hollands, Andrew; Corriden, Ross; Gysler, Gabriela et al. (2016) Natural Product Anacardic Acid from Cashew Nut Shells Stimulates Neutrophil Extracellular Trap Production and Bactericidal Activity. J Biol Chem 291:13964-73
Kuhn, Misty L; Alexander, Evan; Minasov, George et al. (2016) Structure of the Essential Mtb FadD32 Enzyme: A Promising Drug Target for Treating Tuberculosis. ACS Infect Dis 2:579-591
Duckworth, Benjamin P; Wilson, Daniel J; Aldrich, Courtney C (2016) Measurement of Nonribosomal Peptide Synthetase Adenylation Domain Activity Using a Continuous Hydroxylamine Release Assay. Methods Mol Biol 1401:53-61
Park, Sung Ryeol; Tripathi, Ashootosh; Wu, Jianfeng et al. (2016) Discovery of cahuitamycins as biofilm inhibitors derived from a convergent biosynthetic pathway. Nat Commun 7:10710

Showing the most recent 10 out of 516 publications