) Significant disparities in cancer incidence and outcomes exist among ethnic minority populations. Addressing this disparities requires a combined effort from Minority Serving Institutions, and Comprehensive Cancer Centers. The overall goal of this project is to establish a comprehensive long-term partnership between the University of Texas M.D. Anderson Cancer Center (UTMDACC) and the University of Puerto Rico Cancer Center (PRCC) which was initiated three years ago through the support of a P30 grant. Specific objectives of this project include: a) the development of independent investigators through collaborative research projects, b) establishing a stable, long-term collaborative relation between UTMDACC and PRCC in the areas of cancer research, training, and career development, and c) improving the effectiveness of UTMDACC activities designed to benefit the Hispanic population and other minority populations served by the institution. Specifically, efforts will be focused on the development of collaboration in the following areas: 1) Cancer research. Two major and two pilot projects have been identified, 2) Research training. PRCC and UTMDACC will continue the establishment of a comprehensive pipeline program ; 3) Combined infrastructure. Include the frequent use of videoconferences, library services, and establishment of a tissue bank. In addition, a program will be developed which will eventually allow PRCC to establish its own Department of Scientific Publications and Biostatistic Support. Furthermore, this grant will support the recruitment efforts of the PRCC to develop the necessary critical mass in cancer research. By sharing resources and combining the unique strengths and capabilities of the two institutions, it is expected that this collaboration will result in improved research capability, increasing numbers of minority cancer investigators, and more focused and successful attempt to address the disproportionate burden of cancer in Hispanic populations. Both institutions will benefit extremely through the interactions. The extensive interactions will enhance the opportunities for both institutions for apply for SPORES, PC1 and other grants with emphasis on minority/disparity populations. Finally, the one of the major goals of the PRCC is to regain the status of an NCI-designated Cancer Center.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA096297-04
Application #
6935262
Study Section
Special Emphasis Panel (ZCA1-SRRB-7 (J1))
Program Officer
Ogunbiyi, Peter
Project Start
2002-08-16
Project End
2007-07-31
Budget Start
2005-09-09
Budget End
2006-07-31
Support Year
4
Fiscal Year
2005
Total Cost
$1,408,014
Indirect Cost
Name
University of Puerto Rico Med Sciences
Department
Type
Schools of Medicine
DUNS #
948108063
City
San Juan
State
PR
Country
United States
Zip Code
00936
Juan-Rivera, Maylein C; Martínez-Ferrer, Magaly (2018) Integrin Inhibitors in Prostate Cancer. Cancers (Basel) 10:
Cruz-Correa, Marcia; Hylind, Linda M; Marrero, Jessica Hernandez et al. (2018) Efficacy and Safety of Curcumin in Treatment of Intestinal Adenomas in Patients With Familial Adenomatous Polyposis. Gastroenterology 155:668-673
Gonzalez-Mercado, Velda J; Fridley, Brooke L; Saligan, Leorey N (2018) Sestrin family of genes and their role in cancer-related fatigue. Support Care Cancer 26:2071-2074
Villar-Prados, Alejandro; Wu, Sherry Y; Court, Karem A et al. (2018) Predicting novel therapies and targets: Regulation of Notch3 by the bromodomain protein BRD4. Mol Cancer Ther :
Allen, Julie K; Armaiz-Pena, Guillermo N; Nagaraja, Archana S et al. (2018) Sustained Adrenergic Signaling Promotes Intratumoral Innervation through BDNF Induction. Cancer Res 78:3233-3242
Marqués-Lespier, Juan M; Soto-Salgado, Marievelisse; González-Pons, María et al. (2018) Prevalence of Synchronous Oligopolyposis in Incident Colorectal Cancer: A Population-Based Study. P R Health Sci J 37:39-45
Maldonado, María Del Mar; Dharmawardhane, Suranganie (2018) Targeting Rac and Cdc42 GTPases in Cancer. Cancer Res 78:3101-3111
González-Pons, María; Soto-Salgado, Marievelisse; Sevilla, Javier et al. (2018) Seroprevalence of Helicobacter pylori in Hispanics living in Puerto Rico: A population-based study. Helicobacter 23:
Monroig-Bosque, Paloma Del C; Shah, Maitri Y; Fu, Xiao et al. (2018) OncomiR-10b hijacks the small molecule inhibitor linifanib in human cancers. Sci Rep 8:13106
Das, Soma; Parga, Kenia; Chakraborty, Indranil et al. (2018) Magnetic resonance imaging contrast enhancement in vitro and in vivo by octanuclear iron-oxo cluster-based agents. J Inorg Biochem 186:176-186

Showing the most recent 10 out of 157 publications