Significant disparities in cancer incidence and outcomes exist among ethnic minority populations. The overall Goal of this U54 Application is to establish a comprehensive long-term mutually beneficial partnership between the University of Texas M.D. Anderson Cancer Center (MDACC) and the University of Puerto Rico Cancer Center (PRCC). This partnership was initiated three years ago through the support of a supplement to MDACC P30 grant. Specific Objectives of the current proposal include: a) development of independent cancer research investigators through collaborative research projects, and b) establishment of a stable, long-term mutually beneficial collaborative relationship between MDACC and PRCC in the areas of cancer research, training and education. Efforts will be focused on the following areas: 1) Cancer research: the major programs and pilot projects address (a) molecular epidemiology of Head and Neck Cancer, and Breast Cancer, (b) cancer biology related to Breast Cancer, and (c) areas of cancer disparity in minority populations such as Acute Pro-myelocytic Leukemia; 2) Cancer Research training and education programs are described for undergraduate, graduate and post-doctoral students in areas of Cancer Biology, Outreach, and Epidemiology. PRCC and MDACC will continue the establishment of a comprehensive bi-directional training program that will increase the number of Hispanic students interested in cancers in cancer research. In addition, PRCC faculty will receive research training at MDACC; PRCC faculty will increase sensitivity of MDACC faculty to cultural differences among Hispanic groups, a particularly important benefit as Houston's and Texas's Hispanic population continues to grow. Infrastructure activities will include the frequent use of video conferences, library services support, and establishment of a tissue bank. Outstanding individuals agreed to serve as internal advisors and in the Program Steering Committee. The partnership will enhance the opportunities of both institutions to apply for R01s, SPORES, PO1s and R25 Cancer Education grants with an emphasis on reducing cancer disparities among populations. Finally, one of the major long-range goals of the partnership is for PRCC to regain its status as an NCI-designated Cancer Center.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
1U54CA096300-01
Application #
6488638
Study Section
Special Emphasis Panel (ZCA1-SRRB-7 (J1))
Program Officer
Ogunbiyi, Peter
Project Start
2002-08-16
Project End
2007-07-31
Budget Start
2002-08-16
Budget End
2003-07-31
Support Year
1
Fiscal Year
2002
Total Cost
$793,835
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Internal Medicine/Medicine
Type
Other Domestic Higher Education
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Allen, Julie K; Armaiz-Pena, Guillermo N; Nagaraja, Archana S et al. (2018) Sustained Adrenergic Signaling Promotes Intratumoral Innervation through BDNF Induction. Cancer Res 78:3233-3242
Marqués-Lespier, Juan M; Soto-Salgado, Marievelisse; González-Pons, María et al. (2018) Prevalence of Synchronous Oligopolyposis in Incident Colorectal Cancer: A Population-Based Study. P R Health Sci J 37:39-45
Choi, Sangbum; Kang, Sangwook; Huang, Xuelin (2018) Smoothed quantile regression analysis of competing risks. Biom J 60:934-946
González-Pons, María; Soto-Salgado, Marievelisse; Sevilla, Javier et al. (2018) Seroprevalence of Helicobacter pylori in Hispanics living in Puerto Rico: A population-based study. Helicobacter 23:
Monroig-Bosque, Paloma Del C; Shah, Maitri Y; Fu, Xiao et al. (2018) OncomiR-10b hijacks the small molecule inhibitor linifanib in human cancers. Sci Rep 8:13106
Thapa, Bibek; Diaz-Diestra, Daysi; Santiago-Medina, Carlene et al. (2018) T1- and T2-weighted Magnetic Resonance Dual Contrast by Single Core Truncated Cubic Iron Oxide Nanoparticles with Abrupt Cellular Internalization and Immune Evasion. ACS Appl Bio Mater 1:79-89
Xia, Fang; Ning, Jing; Huang, Xuelin (2018) Empirical Comparison of the Breslow Estimator and the Kalbfleisch Prentice Estimator for Survival Functions. J Biom Biostat 9:
Gonzalez, Velda J; McMillan, Susan; Pedro, Elsa et al. (2018) The Health related Quality of Life of Puerto Ricans during Cancer Treatments; A Pilot Study. P R Health Sci J 37:46-51
Gonzalez, Velda J; Abbas-Aghababazadeh, Farnoosh; Fridley, Brooke L et al. (2018) Expression of Sestrin Genes in Radiotherapy for Prostate Cancer and Its Association With Fatigue: A Proof-of-Concept Study. Biol Res Nurs 20:218-226
Yan, Fangrong; Zhu, Huihong; Liu, Junlin et al. (2018) Design and inference for 3-stage bioequivalence testing with serial sampling data. Pharm Stat 17:458-476

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