The Seattle TREC Center organization and administration is designed to optimize the leadership and support to the scientific endeavors of its investigators, five projects, and five cores, and to support the inter- TREC Center collaborations. The Seattle TREC Center will be led by Anne McTiernan, MD, PhD, a Member"""""""" in the FHCRC Public Health Sciences (PHS) Division and Director of the FHCRC Prevention Center. Dr. McTiernan is an international leader in the area of energy balance and cancer, and will provide scientific direction to the Seattle TREC Center in components of energy balance and cancer prevention research. She has conducted seminal work in human exercise intervention studies and cancer biomarkers. Dr. John Potter, MD, PhD, FHCRC Senior Vice President and Director of the PHS Division will co-lead the Center. Dr. Potter, an internationally reknowned leader in nutritional and molecular epidemiology and cancer prevention, has particular strength in working across disciplinary boundaries and integrating data from a variety of models in order to pose specific etiology/prevention questions, and has led several large transdisciplinary research programs including a Program Project Grant focused on the etiology of several gastrointestinal cancer. The major decision-making body of the Seattle TREC Center will be an Executive Committee, which will be comprised of all project and core leaders. The Executive Committee, chaired by Dr. McTiernan, will meet monthly, and will provide scientific oversight and guidance to individual projects including review and approval of protocols, and monitoring progess of individual projects and cores. We will employ several means of fostering transdisciplinary collaborations across the Seattle TREC Center, including the regular Executive Committee meetings, quarterly meetings of the Scientific Program Committee (consisting of all TREC investigators), a seminar series with talks by TREC and other researchers in related areas. Institutional commitments include salary support to key investigators, subsidized laboratories resulting in lower study assay costs, and the unique FHCRC Prevention Center that will provide support to the human .interventions. The Seattle TREC investigators are very experienced with national collaborative studies, and will be eager participants in collaborative interdisciplinary work across the TREC Community.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA116847-05
Application #
7881546
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
2009-09-01
Budget End
2010-08-31
Support Year
5
Fiscal Year
2009
Total Cost
$196,241
Indirect Cost
Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
078200995
City
Seattle
State
WA
Country
United States
Zip Code
98109
Cespedes Feliciano, Elizabeth M; Quante, Mirja; Rifas-Shiman, Sheryl L et al. (2018) Objective Sleep Characteristics and Cardiometabolic Health in Young Adolescents. Pediatrics 142:
Ginos, Bigina N R; Navarro, Sandi L; Schwarz, Yvonne et al. (2018) Circulating bile acids in healthy adults respond differently to a dietary pattern characterized by whole grains, legumes and fruits and vegetables compared to a diet high in refined grains and added sugars: A randomized, controlled, crossover feeding stud Metabolism 83:197-204
Duggan, Catherine; Baumgartner, Richard N; Baumgartner, Kathy B et al. (2018) Genetic variation in TNF?, PPAR?, and IRS-1 genes, and their association with breast-cancer survival in the HEAL cohort. Breast Cancer Res Treat 168:567-576
Duggan, Catherine; Tapsoba, Jean de Dieu; Stanczyk, Frank et al. (2018) Long-term weight loss maintenance, sex steroid hormones, and sex hormone-binding globulin. Menopause :
Citronberg, Jessica S; Curtis, Keith R; White, Emily et al. (2018) Association of gut microbial communities with plasma lipopolysaccharide-binding protein (LBP) in premenopausal women. ISME J 12:1631-1641
Duggan, Catherine; Tapsoba, Jean de Dieu; Wang, Ching-Yun et al. (2017) Long-Term Effects of Weight Loss and Exercise on Biomarkers Associated with Angiogenesis. Cancer Epidemiol Biomarkers Prev 26:1788-1794
Duggan, Catherine; Gross, Myron D; McTiernan, Anne (2017) Diet and Exercise and Serum Markers of Oxidative Stress-Response. Cancer Prev Res (Phila) 10:487
Miles, Fayth L; Navarro, Sandi L; Schwarz, Yvonne et al. (2017) Plasma metabolite abundances are associated with urinary enterolactone excretion in healthy participants on controlled diets. Food Funct 8:3209-3218
Taveras, Elsie M; Rifas-Shiman, Sheryl L; Bub, Kristen L et al. (2017) Prospective Study of Insufficient Sleep and Neurobehavioral Functioning Among School-Age Children. Acad Pediatr 17:625-632
Thompson, Henry J; Neuhouser, Marian L; Lampe, Johanna W et al. (2016) Effect of low or high glycemic load diets on experimentally induced mammary carcinogenesis in rats. Mol Nutr Food Res 60:1416-26

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