Abstract

This renewal proposal is for a center grant for Transdisciplinary Research on Energetics and Cancer (TREC). TREC is a scientific research effort funded by the National Cancer Institute (NCI) aimed at fostering transdisciplinary research on the link between cancer and obesity, diet and physical activity. The purpose of the proposed University of Minnesota center is to renew and broaden a program of transdisciplinary research, training, and outreach/dissemination on energetics and cancer across the life cycle. The proposed center will address questions about obesity and cancer etiology, obesity prevention and weight loss and cancer survival. It will explore biological and behavioral pathways that link energetic to cancer. The center proposal includes three specific research projects;Project 1 will examine the genetic and behavioral etiology of excess weight gain and obesity/cancer risk in infants. It will specifically examine how genetic and socially mediated early life exposures may influence susceptibility to excess weight gain. Project 2 is a study evaluating a novel, community-based intervention to prevent excess weight gain in pre-school aged children, implemented in partnership with early childhood and family education programs in the community. It specifically targets underserved populations. Project 3 is a study of the effects of weight loss on circulating levels of biomarkers associated with cancer recurrence risk and quality of life in obese breast cancer survivors. The potential benefits of weight loss in these women has not been well characterized. Two cores, an Administrative Core and a Bioinformatics and Data Sharing Core, will support the three main projects. The proposal also includes a career development component, substantial funding for developmental projects, and a dissemination/translation component. The overall goals are to advance transdisciplinary science and to advance the understanding of energetic and cancer;to support the career development of new investigators in the field;and to disseminate scientific knowledge about the topic to broader audiences.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
3U54CA116849-05S1
Application #
8135924
Study Section
Special Emphasis Panel (ZCA1-SRRB-Q (M1))
Program Officer
Grant, Yvonne F
Project Start
2005-09-19
Project End
2011-08-31
Budget Start
2009-09-01
Budget End
2011-08-31
Support Year
5
Fiscal Year
2010
Total Cost
$230,000
Indirect Cost

  Institution

Name
University of Minnesota Twin Cities
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
555917996
City
Minneapolis
State
MN
Country
United States
Zip Code
55455

  Publications

Arikawa, Andrea Y; Kaufman, Beth C; Raatz, Susan K et al. (2018) Effects of a parallel-arm randomized controlled weight loss pilot study on biological and psychosocial parameters of overweight and obese breast cancer survivors. Pilot Feasibility Stud 4:17
Marlatt, Kara L; Farbakhsh, Kian; Dengel, Donald R et al. (2016) Breakfast and fast food consumption are associated with selected biomarkers in adolescents. Prev Med Rep 3:49-52
Laska, Melissa N; Hearst, Mary O; Lust, Katherine et al. (2015) How we eat what we eat: identifying meal routines and practices most strongly associated with healthy and unhealthy dietary factors among young adults. Public Health Nutr 18:2135-45
VanKim, Nicole A; Erickson, Darin J; Laska, Melissa N (2015) Food shopping profiles and their association with dietary patterns: a latent class analysis. J Acad Nutr Diet 115:1109-16
Crawford, Talia N; Arikawa, Andrea Y; Kurzer, Mindy S et al. (2015) Cross-sectional study of factors influencing sex hormone-binding globulin concentrations in normally cycling premenopausal women. Fertil Steril 104:1544-51
Arikawa, Andrea Y; Jakits, Holly E; Flood, Andrew et al. (2015) Consumption of a high glycemic load but not a high glycemic index diet is marginally associated with oxidative stress in young women. Nutr Res 35:7-13
Pelletier, Jennifer E; Graham, Dan J; Laska, Melissa N (2014) Social norms and dietary behaviors among young adults. Am J Health Behav 38:144-52
Pelletier, Jennifer E; Laska, Melissa N; Neumark-Sztainer, Dianne et al. (2013) Positive attitudes toward organic, local, and sustainable foods are associated with higher dietary quality among young adults. J Acad Nutr Diet 113:127-32
Graham, Dan J; Pelletier, Jennifer E; Neumark-Sztainer, Dianne et al. (2013) Perceived social-ecological factors associated with fruit and vegetable purchasing, preparation, and consumption among young adults. J Acad Nutr Diet 113:1366-74
Hearst, Mary O; Sirard, John R; Forsyth, Ann et al. (2013) The relationship of area-level sociodemographic characteristics, household composition and individual-level socioeconomic status on walking behavior among adults. Transp Res Part A Policy Pract 50:149-157

Showing the most recent 10 out of 97 publications