The involvement of skilled bioethicists is necessary for the success of research in the basic and translational sciences. In particular, research that is conducted to reduce the burdens caused by the racial disparities in cancer incidence requires bioethical guidance. For these reasons, the Bioethics Shared Resource (BESR) is an integral component of this Partnership. For full/pilot projects, the BESR provides consultation and collaborative support regarding ethical issues from design to implementation and assists in the development of grant proposals, abstracts, and manuscripts. In addition to its work supporting the research of Partnership investigators, the BESR enhances the bioethical capabilities of the Partnership participants. This is accomplished by providing education in bioethics to investigators, junior faculty, post-doctoral fellows, medical residents, graduate/undergraduate and medical students, community health advisors, navigators, partners, and other Partnership personnel regarding sound applications of bioethical principles in cancer research. The BESR provides bioethical education through the Research Education Core of the Partnership and, at TU, collaborates in teaching the graduate/undergraduate courses in bioethics in research, health disparities, and health policy. Bioethics support is essential for enhancing of the basic and translational research of the MSM/TU/UAB CCC Partnership.

Public Health Relevance

The Bioethics Shared Resource (BESR), coordinated through the Tuskegee University (TU) National Center for Bioethics in Health Care Research, will provide bioethics education, training, guidance, and consultation throughout the Morehouse School of Medicine/TU/the University of Alabama at Birmingham Comprehensive Cancer Center Partnership. Achieving appropriate bioethical competencies and integration ensures that research projects, outreach, and partnering with underserved and racial/ethnic minorities follow ethical guidelines.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA118623-12
Application #
9358688
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
2017-09-01
Budget End
2018-08-31
Support Year
12
Fiscal Year
2017
Total Cost
Indirect Cost
Name
Tuskegee University
Department
Type
DUNS #
128214178
City
Tuskegee Institute
State
AL
Country
United States
Zip Code
36088
Akintobi, Tabia Henry; Lockamy, Elise; Goodin, Lisa et al. (2018) Processes and Outcomes of a Community-Based Participatory Research-Driven Health Needs Assessment: A Tool for Moving Health Disparity Reporting to Evidence-Based Action. Prog Community Health Partnersh 12:139-147
Angajala, Anusha; Mothershed, Essynce; Davis, Melissa B et al. (2018) Quadruple Negative Breast Cancers (QNBC) Demonstrate Subtype Consistency among Primary and Recurrent or Metastatic Breast Cancer. Transl Oncol 12:493-501
Davis, Melissa; Tripathi, Shweta; Hughley, Raymond et al. (2018) AR negative triple negative or ""quadruple negative"" breast cancers in African American women have an enriched basal and immune signature. PLoS One 13:e0196909
Angajala, Anusha; Lim, Sangbin; Phillips, Joshua B et al. (2018) Diverse Roles of Mitochondria in Immune Responses: Novel Insights Into Immuno-Metabolism. Front Immunol 9:1605
Abisoye-Ogunniyan, Abisola; Lin, Huxian; Ghebremedhin, Anghesom et al. (2018) Transcriptional repressor Kaiso promotes epithelial to mesenchymal transition and metastasis in prostate cancer through direct regulation of miR-200c. Cancer Lett 431:1-10
Mukherjee, Angana; Hollern, Daniel P; Williams, Oluwasina G et al. (2018) A Review of FOXI3 Regulation of Development and Possible Roles in Cancer Progression and Metastasis. Front Cell Dev Biol 6:69
Yates, Clayton; Long, Mark D; Campbell, Moray J et al. (2017) miRNAs as drivers of TMPRSS2-ERG negative prostate tumors in African American men. Front Biosci (Landmark Ed) 22:212-229
Piyathilake, Chandrika J; Badiga, Suguna; Borak, Samuel G et al. (2017) A higher degree of expression of DNA methyl transferase 1 in cervical cancer is associated with poor survival outcome. Int J Womens Health 9:413-420
Chen, Ina; Mathews-Greiner, Lesley; Li, Dandan et al. (2017) Transcriptomic profiling and quantitative high-throughput (qHTS) drug screening of CDH1 deficient hereditary diffuse gastric cancer (HDGC) cells identify treatment leads for familial gastric cancer. J Transl Med 15:92
Afolabi, Michael O S; Sodeke, Stephen O (2017) A Multifaceted Approach Is Needed to Respond to the Plight of Bioethicists in Accessing Literature. Am J Bioeth 17:37-39

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