Biostatistics CoreA biostatistics core will be led by Dr. Feng Gao, Division of Biostatistics, Washington University School ofMedicine. The role of biostatics core will be to lower the barriers to the incorporation of biostatistics to all levelsof the translational research office, thereby ensuring that all of the NTR Center investigators will have accessto high quality biostatistics input into their clinical and translational research projects from the start.Incorporating a biostatistical review early in study designs will ensure that the studies meet high standards ofdesign and biostatistics. Increased support for methodological research will assure that appropriate methodswill be developed to address the evolving challenges of rapidly changing translational research opportunities.Biostatistics Core of the Siteman Cancer Center frequently provides informatics services. These range fromthe manipulation and merging of existing electronic data sets to the creation of data entry systems. TheDivision of Biostatistics has considerable expertise in this area, particularly in its role as a coordinating centerfor diverse multi-institutional NIH-sponsored studies, or as a core for intramural centers and projects. TheDivision is a leader in the development of distributed data entry services. The current approach is a thin-clientmodel with the use of a web browser on the client end and a web-server centrally. The standard programmingenvironment for data management, statistical analysis and information delivery is SAS, and these web-baseddata entry systems are implemented with the SAS/lntrNet product.In order to support a wide variety of studies within the Siteman Cancer Center, the Core has collaboratedwith the Clinical Trials Core and with SAS Institute to create the Siteman Clinical Information Portal (SCIP).SCIP was created by customizing a previously-developed suite of browser-based form design tools. SCIPallows for the creation and management of data collection instruments by nonprogrammers and supports webbaseddata entry and editing.
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