Core D: Biostatistics - The Biostatistics Core consists of personnel with expertise in statistics and clinical informatics, including Drs T Johnson, P Schoenfeld, and B Athey. The goal of this Core is to collaborate with NTR investigators and other network scientists to enhance the rigor, quality, and safety of the research data. The Core personnel have been chosen because of their expertise in biostatistics and informatics, and their knowledge of gastrointestinal cancer screening. Biostatistics core personnel will collaborate with investigators in the Primary and Task Specific projects, and will work with the other Cores to provide support in all stages of the research, beginning with the formulation of the research question, and continuing through experimental design, data collection, storage, and archival, data analysis and interpretation, and writing of manuscripts.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA136429-03
Application #
8132374
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
2010-09-01
Budget End
2011-08-31
Support Year
3
Fiscal Year
2010
Total Cost
$17,630
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
073133571
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Joshi, Bishnu P; Duan, Xiyu; Kwon, Richard S et al. (2016) Multimodal endoscope can quantify wide-field fluorescence detection of Barrett's neoplasia. Endoscopy 48:A1-A13
Joshi, Bishnu P; Pant, Asha; Duan, Xiyu et al. (2016) Multimodal Video Colonoscope for Targeted Wide-Field Detection of Nonpolypoid Colorectal Neoplasia. Gastroenterology 150:1084-1086
Zhou, Juan; Joshi, Bishnu P; Duan, Xiyu et al. (2015) EGFR Overexpressed in Colonic Neoplasia Can be Detected on Wide-Field Endoscopic Imaging. Clin Transl Gastroenterol 6:e101
Khondee, Supang; Rabinsky, Emily F; Owens, Scott R et al. (2015) Targeted therapy of colorectal neoplasia with rapamycin in peptide-labeled pegylated octadecyl lithocholate micelles. J Control Release 199:114-21
Atreya, Raja; Neumann, Helmut; Neufert, Clemens et al. (2014) In vivo imaging using fluorescent antibodies to tumor necrosis factor predicts therapeutic response in Crohn's disease. Nat Med 20:313-8
Qiu, Zhen; Khondee, Supang; Duan, Xiyu et al. (2014) Vertical cross-sectional imaging of colonic dysplasia in vivo with multi-spectral dual axes confocal endomicroscopy. Gastroenterology 146:615-7
Khondee, Supang; Wang, Thomas D (2013) Progress in molecular imaging in endoscopy and endomicroscopy for cancer imaging. J Healthc Eng 4:1-22
Sturm, Matthew B; Piraka, Cyrus; Elmunzer, B Joseph et al. (2013) In vivo molecular imaging of Barrett's esophagus with confocal laser endomicroscopy. Gastroenterology 145:56-58
Liu, Zhongyao; Miller, Sharon J; Joshi, Bishnu P et al. (2013) In vivo targeting of colonic dysplasia on fluorescence endoscopy with near-infrared octapeptide. Gut 62:395-403
Sturm, Matthew B; Joshi, Bishnu P; Lu, Shaoying et al. (2013) Targeted imaging of esophageal neoplasia with a fluorescently labeled peptide: first-in-human results. Sci Transl Med 5:184ra61

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