The long-term objective of this project is to bring to clinical practice a novel technology for the real-time and non-invasive measurement of cancer-related analytes. This technology consists of a sensor implanted at the time of a tumor biopsy to allow subsequent monitoring of tumor analytes such as pH and p02 through magnetic resonance methods.
The specific aims of the project are as follows: design and execute preclinical studies in support of a Premarl
Existing technology that assesses cancer treatment efficacy is cumbersome, costly and in the case of pH and p02, highly invasive. Approval ofthe pH and p02 sensors for commercialization will not only improve clinical care by providing the oncologist with a real-time and non-invasive monitoring tool, but will allow the development of a versatile technological platform capable of detecting any analyte with the appropriate sensing agent.
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