South Carolina Cancer Disparities Community Network-ll builds upon the many successes we achieved as a Community Networks Program funded in CNP-I. SCCDCN-ll's overarching goal is to contribute materially to: understanding the underiying causes of cancer-related health disparities;discovering and developing effective innovations to lower incidence, improve survival, and reduce suffering;delivering these innovations to high-risk populations;and, finally, moving them to widespread dissemination. We focus on African Americans (AAs) in South Carolina, a group in a region with much higher-than-average cancer incidence and extraordinarily high mortality given incidence. Our goal will be realized by achieving these Specific Aims: 1. To use the full range of expertise represented in our academic and community partnerships, to increase the knowledge base needed to understand which biomedical and behavioral procedures are most likely to prevent and control cancer in the high-risk African-American communities in South Carolina; 2. Based on discoveries derived from thorough understanding ofthe literature, careful consideration of our own descriptive studies and observations, and feedback from community partners, to develop and test interventions that are likely to reduce cancer incidence, downstage disease at time of diagnosis, increase longevity, and improve gualitv of life in people with cancer; 3. To deliver interventions shown to be effective to places of greatest receptivity and public health need and to evaluate them in terms of generalizability (i.e., external validity);and 4. To disseminate results from successful interventions in the form of intervention """"""""packages"""""""" within our communities in South Carolina and to work with national partners to determine and distinguish universal elements that will work most (or at least many) places and others that are more place- and culture-specific. The success of SCCDCN-ll is predicated on: strong community support;dedication to the principles of community-based participatory research;understanding that the philosophical underpinnings and practical methods of applying knowledge are essentially the same across interdisciplinary, translational and communitybased participatory research;that the tripartite missions of research, education, and service are both inseparable and highly interdependent;and that training ofthe next generation of scientists dedicated to the highest ideals of community-based participatory, interdisciplinary, and translational research is necessary in order to reduce, and then finally eliminate cancer-related health disparities.

National Institute of Health (NIH)
National Cancer Institute (NCI)
Specialized Center--Cooperative Agreements (U54)
Project #
Application #
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of South Carolina at Columbia
United States
Zip Code
Felder, Tisha M; Braun, Kathryn L; Wigfall, Lisa et al. (2018) Mentoring, Training, and Scholarly Productivity Experiences of Cancer-Related Health Disparities Research Trainees: Do Outcomes Differ for Underrepresented Scientists? J Cancer Educ :
Bevel, Malcolm; Babatunde, Oluwole A; Heiney, Sue P et al. (2018) Sistas Inspiring Sistas Through Activity and Support (SISTAS): Study Design and Demographics of Participants. Ethn Dis 28:75-84
Alexander, M; Burch, J B; Steck, S E et al. (2017) Case-control study of candidate gene methylation and adenomatous polyp formation. Int J Colorectal Dis 32:183-192
Wigfall, Lisa T; Bynum Mph, Shalanda A; Friedman, Daniela B et al. (2017) Patient-provider communication with HIV-positive women about abnormal Pap test results. Women Health 57:19-39
Wirth, M D; Shivappa, N; Davis, L et al. (2017) Construct Validation of the Dietary Inflammatory Index among African Americans. J Nutr Health Aging 21:487-491
H├ębert, James R; Frongillo, Edward A; Adams, Swann A et al. (2016) Perspective: Randomized Controlled Trials Are Not a Panacea for Diet-Related Research. Adv Nutr 7:423-32
Shoaibi, Azza; Rao, Gowtham A; Cai, Bo et al. (2016) The use of multiphase nonlinear mixed models to define and quantify long-term changes in serum prostate-specific antigen: data from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Ann Epidemiol 26:36-42.e1-2
Friedman, Daniela B; Wilcox, Sara; Hebert, James R (2016) Proposing an Interdisciplinary, Communication-Focused Agenda for Cancer and Aging Researchers. J Cancer Educ 31:218-20
Owens, Otis L; Friedman, Daniela B; Brandt, Heather M et al. (2016) Digital Solutions for Informed Decision Making: An Academic-Community Partnership for the Development of a Prostate Cancer Decision Aid for African American Men. Am J Mens Health 10:207-19
Wigfall, L T; Bynum, S A; Brandt, H M et al. (2016) HPV Vaccine Awareness and Knowledge Among Women Living with HIV. J Cancer Educ 31:187-90

Showing the most recent 10 out of 54 publications