The objectives to expand the Ponce School of Medicine-Moffitt Cancer Center Partnership are to: 1) Maintain a comprehensive administrative infrastructure and procedures to perform critical evaluations of the projects and cores, solve problems, maintain quality, and strategically plan for continued expansion of the Partnership, and provide support for the development of the successful careers of the Partnership faculty. 2) Bring together in close collaboration basic scientists at PSM and MCC to conduct research projects: this will provide scientists at PSM access to experienced cancer research scientists as collaborators and mentors as well as advanced technologies, to advance their careers and the impact of their science. Reciprocally, the MCC scientists will benefit from becoming involved in new research projects focused on the unique biology of Hispanic patient cancers. 3) Develop a comprehensive training pipeline to produce a cadre of cancer translational research scientists, both basic and clinical, to address the shortage of Hispanic academicians on the faculties of academic health centers in Puerto Rico and the mainland US. This will produce scientists who are knowledgeable about the issues related to Hispanic cancer health disparities and motivated to perform research to address these disparities. 4) Conduct rigorous outreach research to learn the most effective ways of communicating cancer related information, and expand community outreach programs incorporating these discoveries. This will improve participation in clinical research and biobanking, and the overall health of the Hispanic community in Florida served by the MCC and in Puerto Rico. 5) Expand at the PSM tertiary referral clinical oncology services, educational opportunities for community oncologists and oncology fellows, and patient access to clinical trials to improve cancer care for the currently underserved population of Southwest Puerto Rico. 6) Establish for the first time a high quality tumor bank of tissues from Puerto Rican cancer patients that will provide a unique and valuable resource for the basic research scientists to make discoveries that are specific for Hispanic cancer patients that will provide insight for th development of biomarker driven personalized medicine for this population.

Public Health Relevance

The continued academic partnership between the PSM and the MCC will lead to improved outcomes for Hispanic cancer patients in Puerto Rico and Florida who are currently underserved with respect to cancer care, personalized medicine, and participation in clinical research.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54CA163071-03
Application #
8728152
Study Section
Special Emphasis Panel (ZCA1)
Program Officer
Ogunbiyi, Peter
Project Start
2012-09-25
Project End
2017-08-31
Budget Start
2014-09-01
Budget End
2015-08-31
Support Year
3
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Ponce School of Medicine
Department
Type
DUNS #
City
Ponce
State
PR
Country
United States
Zip Code
00732
Rivera, Y M; Moreno, L; Briant, K J et al. (2018) Developing Sustainable Cancer Education Programs: Training Public Health Students to Deliver Cancer 101 in Puerto Rico. J Cancer Educ 33:128-133
Rodriguez-Velazquez, Ariel; Velez, Rosa; Lafontaine, Jean Carlo et al. (2018) Prevalence of breast and ovarian cancer subtypes in Hispanic populations from Puerto Rico. BMC Cancer 18:1177
Gjyshi, Anxhela; Dash, Sweta; Cen, Ling et al. (2018) Early transcriptional response of human ovarian and fallopian tube surface epithelial cells to norepinephrine. Sci Rep 8:8291
Jiménez-Chávez, Julio C; Rosario-Maldonado, Fernando J; Torres, Jeremy A et al. (2018) Assessing Acceptability, Feasibility, and Preliminary Effectiveness of a Community-Based Participatory Research Curriculum for Community Members: A Contribution to the Development of a Community-Academia Research Partnership. Health Equity 2:272-281
Jusino, Shirley; Fernández-Padín, Fabiola M; Saavedra, Harold I (2018) Centrosome aberrations and chromosome instability contribute to tumorigenesis and intra-tumor heterogeneity. J Cancer Metastasis Treat 4:
King, Jamie L; Zhang, Baotong; Li, Yixiang et al. (2018) TTK promotes mesenchymal signaling via multiple mechanisms in triple negative breast cancer. Oncogenesis 7:69
Bonilla-Valentín, Fernando Javier; Cerra, Javier; Cáceres-Perkins, William et al. (2018) Case Report of IgM Multiple Myeloma: Diagnosing a Rare Hematologic Entity. Cancer Control 25:1073274817744448
Pérez-Morales, Jaileene; Núñez-Marrero, Angel; Santiago-Cardona, Pedro G (2018) Immunohistochemical Detection of Retinoblastoma Protein Phosphorylation in Human Tumor Samples. Methods Mol Biol 1726:77-84
Dutil, Julie; Godoy, Lenin; Rivera-Lugo, Rafael et al. (2018) No Evidence for the Pathogenicity of the BRCA2 c.6937?+?594T>G Deep Intronic Variant: A Case-Control Analysis. Genet Test Mol Biomarkers 22:85-89
Reverón, Dayana; López, Christian; Gutiérrez, Sylvia et al. (2018) Frequency of Mismatch Repair Protein Deficiency in a Puerto Rican Population with Colonic Adenoma and Adenocarcinoma. Cancer Genomics Proteomics 15:265-271

Showing the most recent 10 out of 62 publications