Outreach Core all career stages. It will put in place many activities to build and enhance the cohesion of the Center. Such activities include a seminar series in which graduate students and postdocs share their research in progress, a Distinguished Speaker series, that will bring leading researchers in the Systems Biology of Cancer to the Center, an annual Symposium, focused single topic workshops and hands on summer schools. In addition, the Outreach core will co-ordinate with the cores at other Centers in the Consortium, to build and sustain interactions between different centers. Researchers at other Centers in the Consortium will be invited to participate in the focused single topic workshops and the summer schools. Moreover, the Center will facilitate short visits by researchers, too and from different Centers in the Consortium, for collaborative work, or to learn new methods. The outreach core will be responsible for the Center's web page, which will be used to disseminate results and resources to the wider scientific community. The Outreach core will also lead broader impact outreach endeavors by all Center members, at every career stage. The leadership of the Outreach core will expedite Center members' participation in Organizations at Yale with established infrastructures for such activities. The Outreach core will also work individually with Center researchers to develop and fine-tune any new broader impact outreach activities that they devise. The Outreach core will also lead and oversee the placement of high-school interns and undergraduate students from under-represented groups into Center labs for hands on research emersion during the summer. A key mission of the Outreach core is to promote excellence in the communication of science. The ability to communicate their science clearly to other researchers is of vital importance to all Center members. In addition, the Center is committed to enhancing the ability of its scientists to communicate to the general public. Towards fulfilling this goal, the Outreach core will sponsor a unique short communications course, taught by Bob Bazel (former head of science reporting at NBC, now an adjunct professor at Yale). The overarching goal of the Outreach core is to seamlessly integrate all these activities into the fabric of the Center. The Outreach Core will coordinate the multiple Center activities that promote cancer systems biology at

National Institute of Health (NIH)
National Cancer Institute (NCI)
Specialized Center--Cooperative Agreements (U54)
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Special Emphasis Panel (ZCA1-RTRB-R (M1))
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Yale University
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Chatterjee, Meenakshi; Acar, Murat (2018) Heritable stress response dynamics revealed by single-cell genealogy. Sci Adv 4:e1701775
Ye, Lupeng; Wang, Chengkun; Hong, Lingjuan et al. (2018) Programmable DNA repair with CRISPRa/i enhanced homology-directed repair efficiency with a single Cas9. Cell Discov 4:46
Chow, Ryan D; Chen, Sidi (2018) Cancer CRISPR Screens In Vivo. Trends Cancer 4:349-358
Xue, Yuan; Acar, Murat (2018) Mechanisms for the epigenetic inheritance of stress response in single cells. Curr Genet 64:1221-1228
Luo, Xinyue; Song, Ruijie; Acar, Murat (2018) Multi-component gene network design as a survival strategy in diverse environments. BMC Syst Biol 12:85
Chow, Ryan D; Chen, Sidi (2018) Sno-derived RNAs are prevalent molecular markers of cancer immunity. Oncogene 37:6442-6462
Chow, Ryan D; Kim, Hyunu Ray; Chen, Sidi (2018) Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion. Nat Commun 9:1903
Gaines, J C; Acebes, S; Virrueta, A et al. (2018) Comparing side chain packing in soluble proteins, protein-protein interfaces, and transmembrane proteins. Proteins 86:581-591
Elison, Gregory L; Xue, Yuan; Song, Ruijie et al. (2018) Insights into Bidirectional Gene Expression Control Using the Canonical GAL1/GAL10 Promoter. Cell Rep 25:737-748.e4
Vanaja, Kiran G; Timp, Winston; Feinberg, Andrew P et al. (2018) A Loss of Epigenetic Control Can Promote Cell Death through Reversing the Balance of Pathways in a Signaling Network. Mol Cell 72:60-70.e3

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