This proposed NYU Oral Cancer Research for Adolescent and Adult Health Promotion (RAAHP) Center is a P50 Center which was designed in response to the NIDCR request for applications for Centers for Research to Reduce Oral Health Disparities (RFA:DE-99-003). The overall goal of this proposed NY Oral Cancer RAAHP Center is to conduct studies and promote activities that will reduce oral disparities in the United States. While oral cancer occurs in all segments of the U.S. population, oral cancer rates (both incidence and mortality) are highest among minority populations, especially in African Americans and in Hispanics. Specifically, this proposed Center will, as stated in the RFA, support research """"""""that will lead to an understanding of the factors associated with health disparities as well as to the support and development, testing and evaluation of interventions designed to reduce [oral cancer] disparities"""""""".
The Specific Aims of the overall Center are: 1) to conduct a set of five major studies, as fully described in this grant application; 2) to design and conduct a sixth major study on oral cancer in the theme of this Center; 3.) to stimulate and support the design, writing and submission of Developmental 'Spin-Off'; 4.) to stimulate and support the development, selection, funding and implementation of two types of pilot research studies: bioethics and scientific pilot studies; 5.) to maintain three Cores (Administrative, Informatics, and Biostatistics) that will support the scientific activities of all the investigators in this proposed Center; 6) to develop and implement a full set of intra-Center research training and career development activities which focus on creating opportunities for scientists from underrepresented groups within the scientific workforce; 7) to participate fully in inter-Center national research and training networks; 8) to serve as an intellectual and administrative nidus to stimulate oral cancer research interests, discussions, and planning sessions among Center participants as well as among other cancer research colleagues; and 9) to provide information and findings on oral cancer to community involved health service units.

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54DE014257-02
Application #
6524226
Study Section
Special Emphasis Panel (ZDE1-GH (03))
Program Officer
Nowjack-Raymer, Ruth
Project Start
2001-09-30
Project End
2008-07-31
Budget Start
2002-08-01
Budget End
2003-07-31
Support Year
2
Fiscal Year
2002
Total Cost
$1,130,291
Indirect Cost
Name
New York University
Department
Other Basic Sciences
Type
Schools of Dentistry
DUNS #
004514360
City
New York
State
NY
Country
United States
Zip Code
10012
Acharya, Amit; Hernandez, Pedro; Thyvalikakath, Thankam et al. (2013) Development and initial validation of a content taxonomy for patient records in general dentistry. Int J Med Inform 82:1171-82
Erdei, Esther; Luo, Li; Sheng, Huiping et al. (2013) Cytokines and tumor metastasis gene variants in oral cancer and precancer in Puerto Rico. PLoS One 8:e79187
Schussel, Juliana; Zhou, Xian Chong; Zhang, Zhe et al. (2013) EDNRB and DCC salivary rinse hypermethylation has a similar performance as expert clinical examination in discrimination of oral cancer/dysplasia versus benign lesions. Clin Cancer Res 19:3268-75
Davis, Jenna L; Green, B Lee; Katz, Ralph V (2012) Influence of scary beliefs about the Tuskegee Syphilis Study on willingness to participate in research. ABNF J 23:59-62
Sun, Wenyue; Zaboli, David; Liu, Yan et al. (2012) Comparison of promoter hypermethylation pattern in salivary rinses collected with and without an exfoliating brush from patients with HNSCC. PLoS One 7:e33642
Davis, Jenna L; Buchanan, Kyrel L; Katz, Ralph V et al. (2012) Gender differences in cancer screening beliefs, behaviors, and willingness to participate: implications for health promotion. Am J Mens Health 6:211-7
Davis, Jenna L; Bynum, Shalanda A; Katz, Ralph V et al. (2012) Sociodemographic differences in fears and mistrust contributing to unwillingness to participate in cancer screenings. J Health Care Poor Underserved 23:67-76
Bynum, Shalanda A; Davis, Jenna L; Green, B Lee et al. (2012) Unwillingness to participate in colorectal cancer screening: examining fears, attitudes, and medical mistrust in an ethnically diverse sample of adults 50 years and older. Am J Health Promot 26:295-300
Sun, Wenyue; Zaboli, David; Wang, Hao et al. (2012) Detection of TIMP3 promoter hypermethylation in salivary rinse as an independent predictor of local recurrence-free survival in head and neck cancer. Clin Cancer Res 18:1082-91
Russell, Stefanie L; Katz, Ralph V; Wang, Min Qi et al. (2011) Belief in AIDS origin conspiracy theory and willingness to participate in biomedical research studies: findings in whites, blacks, and Hispanics in seven cities across two surveys. HIV Clin Trials 12:37-47

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