Diffusion tensor imaging can measure the microstructural integrity and orientational structure of nerve tissue. Computational tools to extract microstructural information from DTI will enhance insight into neuroanatomy, neuropathology, and neuropsychiatric disorders. We propose to develop statistical tools to test group-level hypotheses on white matter histoarchitecture based on diffusion imaging. We will extend analytic and statistical tools developed for scalar data, to orientational diffusion data, leading to improved registration, segmentation, and analysis of tissue microstructure.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54EB005149-04
Application #
7479769
Study Section
Special Emphasis Panel (ZRG1)
Project Start
Project End
Budget Start
2007-08-01
Budget End
2008-07-31
Support Year
4
Fiscal Year
2007
Total Cost
$314,294
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
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