Abstract

Core 3: Clinical Needs Assessment and Dissemination Introduction Better access to diagnostic testing is essential to improving the health of underserved populations in LRS around the world. One approach to improve access to affordable and appropriate diagnostic technologies is by developing tests specifically designed for use at POC. We therefore are proposing a Center that is organized around the theme of POC diagnostics for LRS. For the purposes of this Center, we define LRS as regions where health care is poor or even nonexistent. In Core 3, the Center will define the need for and the value of POC diagnostics in LRS.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Specialized Center--Cooperative Agreements (U54)
Project #
5U54EB007949-03
Application #
7886714
Study Section
Special Emphasis Panel (ZEB1)
Project Start
Project End
Budget Start
2009-07-01
Budget End
2010-06-30
Support Year
3
Fiscal Year
2009
Total Cost
$185,303
Indirect Cost

  Institution

Name
Program/Appropriate/Technology/Health
Department
Type
DUNS #
103713624
City
Seattle
State
WA
Country
United States
Zip Code
98121

  Publications

Pollock, Nira R; McGray, Sarah; Colby, Donn J et al. (2013) Field evaluation of a prototype paper-based point-of-care fingerstick transaminase test. PLoS One 8:e75616
Byrnes, Samantha; Fan, Andy; Trueb, Jacob et al. (2013) A Portable, Pressure Driven, Room Temperature Nucleic Acid Extraction and Storage System for Point of Care Molecular Diagnostics. Anal Methods 5:3177-3184
Fan, Andy; Byrnes, Samantha; Klapperich, Catherine (2013) Purification of DNA/RNA in a microfluidic device. Methods Mol Biol 949:403-11
Stevens, Daniel S; Crudder, Christopher H; Domingo, Gonzalo J (2012) Post-extraction stabilization of HIV viral RNA for quantitative molecular tests. J Virol Methods 182:104-10
Palamountain, Kara M; Baker, Jeff; Cowan, Elliot P et al. (2012) Perspectives on introduction and implementation of new point-of-care diagnostic tests. J Infect Dis 205 Suppl 2:S181-90
Boyle, David S; Hawkins, Kenneth R; Steele, Matthew S et al. (2012) Emerging technologies for point-of-care CD4 T-lymphocyte counting. Trends Biotechnol 30:45-54
Weigl, Bernhard H; Gaydos, Charlotte A; Kost, Gerald et al. (2012) The Value of Clinical Needs Assessments for Point-of-Care Diagnostics. Point Care 11:108-113
Dragan, A I; Geddes, C D (2011) Excitation volumetric effects (EVE) in metal-enhanced fluorescence. Phys Chem Chem Phys 13:3831-8
Barfield, C A; Barney, R S; Crudder, C H et al. (2011) A highly sensitive rapid diagnostic test for Chagas disease that utilizes a recombinant Trypanosoma cruzi antigen. IEEE Trans Biomed Eng 58:814-7
LaBarre, Paul; Hawkins, Kenneth R; Gerlach, Jay et al. (2011) A simple, inexpensive device for nucleic acid amplification without electricity-toward instrument-free molecular diagnostics in low-resource settings. PLoS One 6:e19738

Showing the most recent 10 out of 14 publications